Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1806045..1807553 Replicon chromosome
Accession NZ_CP041354
Organism Pseudomonas aeruginosa strain AZPAE15042

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag IHMA87_RS08565 Protein ID WP_079383582.1
Coordinates 1806045..1806632 (+) Length 196 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag IHMA87_RS08570 Protein ID WP_034082037.1
Coordinates 1806699..1807553 (+) Length 285 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHMA87_RS08560 1802300..1805779 - 3480 WP_012074951.1 hybrid sensor histidine kinase/response regulator -
IHMA87_RS08565 1806045..1806632 + 588 WP_079383582.1 GNAT family N-acetyltransferase Toxin
IHMA87_RS08570 1806699..1807553 + 855 WP_034082037.1 AraC family transcriptional regulator Antitoxin
IHMA87_RS08575 1807649..1809814 + 2166 WP_034082040.1 TonB-dependent receptor family protein -
IHMA87_RS08580 1809989..1811863 + 1875 WP_034082042.1 MFS transporter -
IHMA87_RS08585 1811924..1812133 - 210 WP_003091604.1 cold-shock protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(20-152)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(19-147)


Sequences

Toxin        


Download         Length: 196 a.a.        Molecular weight: 21862.19 Da        Isoelectric Point: 9.8675

>T128155 WP_079383582.1 NZ_CP041354:1806045-1806632 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQGIADQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQFSTAASNLRAQGAIDKLGAQREGLLRN
QRRLAGGRLDDTIVYSITDHEWPQVKAALEASFTG

Download         Length: 588 bp

>T128155 NZ_CP041354:1806045-1806632 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGTGGAGCCTTGCGGCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTTGCCGAAGCCAACCGCGAGGCACTGCAGTACATGGACGGACCGACGCGCCCGG
ACTGGTATCGCCAGGGCATCGCCGACCAGCGCGAGGGACGCGCGTTGCCGCTGGCGGTACGCCTGGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAATTCCTTCCCGCCCTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGT
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCCCAGCGCGAGGGCCTGCTGCGCAAC
CAGCGGCGCCTGGCCGGCGGGCGTCTCGACGACACCATCGTCTACAGCATCACCGACCACGAGTGGCCCCAGGTCAAAGC
CGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 285 a.a.        Molecular weight: 31732.08 Da        Isoelectric Point: 8.0066

>AT128155 WP_034082037.1 NZ_CP041354:1806699-1807553 [Pseudomonas aeruginosa]
VPDETSGEHTHFWRAAALGGVELLHARYVEQRFAPHVHSGFALVFIEQGAQRFRHRGGEHLAPWGSMVLINPDEVHTGSK
AHDSGWLYRGYYPEVEQIASVLDELEIRHGGVPRFADSVVHDQPLARAFVHLHRLLADHAGSLETQTCWRETLLALFRRH
ARLPEAPKAGSEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMLPHAWLRQRRLEQARALLKNGRA
PLDVALELGFADQSHLGRQFKQAYGVAPGEYRAACARSSLTMCE

Download         Length: 855 bp

>AT128155 NZ_CP041354:1806699-1807553 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACATACGCATTTCTGGCGCGCCGCCGCACTGGGCGGCGTCGAGTTGCTGCATGCGCG
CTACGTCGAGCAGCGTTTCGCCCCCCATGTGCACAGCGGCTTCGCCCTGGTCTTCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGCGGCGGCGAGCACCTGGCGCCCTGGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCATACCGGCTCCAAG
GCCCATGACTCCGGCTGGCTCTATCGCGGCTATTACCCGGAAGTGGAGCAGATCGCCAGTGTCCTCGACGAGCTGGAAAT
CCGCCACGGCGGGGTGCCGCGTTTCGCCGACAGCGTGGTCCATGACCAGCCCCTGGCGCGCGCCTTCGTCCATCTGCACC
GCTTGCTGGCCGACCACGCCGGCAGCTTGGAAACCCAGACCTGCTGGCGCGAGACGCTGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCGGAGGCGCCGAAGGCCGGGTCGGAACCGCTGGCGGTCGCCCGCGCCCGCGAGTTGCTGGCGGCGCGTTT
GCTCGACCCGCCGTCGCTGGAAGAACTGGCGGCTGCGGTGAACCTGTCGCCGTTCCACTTCGCCCGGGTGTTCCGCCGCG
CCACCGGGATGCTGCCGCATGCCTGGCTCCGGCAACGGCGCCTGGAGCAGGCCAGGGCGCTGCTCAAGAATGGCCGGGCG
CCGCTGGATGTCGCCCTGGAACTGGGCTTCGCCGACCAGAGCCATCTCGGTCGCCAGTTCAAGCAGGCCTACGGCGTGGC
GCCGGGCGAGTACCGCGCGGCCTGTGCGCGCTCGTCCTTGACGATGTGCGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References