Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1894180..1894325 Replicon chromosome
Accession NZ_CP041353
Organism Klebsiella pneumoniae strain RJY9645

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1894216..1894318 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1894180..1894325 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJR44_RS09085 1889310..1891370 + 2061 WP_004148850.1 oligopeptidase B -
FJR44_RS09090 1891374..1892033 - 660 WP_065799440.1 exodeoxyribonuclease X -
FJR44_RS09095 1892112..1892342 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FJR44_RS09100 1892455..1892829 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FJR44_RS09105 1892833..1893702 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
FJR44_RS09110 1893719..1894057 + 339 WP_002911404.1 YebY family protein -
- 1894180..1894325 - 146 - - Antitoxin
- 1894216..1894318 + 103 - - Toxin
FJR44_RS09115 1894693..1894836 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FJR44_RS09120 1894941..1895909 - 969 WP_014907334.1 VirK/YbjX family protein -
FJR44_RS09125 1896066..1896719 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
FJR44_RS09130 1896716..1896907 - 192 WP_002911395.1 YebW family protein -
FJR44_RS09135 1897005..1897244 - 240 WP_002911393.1 YebV family protein -
FJR44_RS09140 1897360..1898793 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T128139 NZ_CP041353:1894216-1894318 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT128139 NZ_CP041353:c1894325-1894180 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References