Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 2431708..2432475 Replicon chromosome
Accession NZ_CP041352
Organism Casimicrobium huifangae strain SJ-1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag FKL89_RS11010 Protein ID WP_156862798.1
Coordinates 2431990..2432475 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag FKL89_RS11005 Protein ID WP_156862797.1
Coordinates 2431708..2431986 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FKL89_RS10990 2427036..2428574 - 1539 WP_156862794.1 hypothetical protein -
FKL89_RS10995 2428751..2430334 + 1584 WP_156862795.1 type I restriction-modification system subunit M -
FKL89_RS11000 2430324..2431622 + 1299 WP_156862796.1 restriction endonuclease subunit S -
FKL89_RS11005 2431708..2431986 + 279 WP_156862797.1 DUF1778 domain-containing protein Antitoxin
FKL89_RS11010 2431990..2432475 + 486 WP_156862798.1 GNAT family N-acetyltransferase Toxin
FKL89_RS11015 2432472..2435636 + 3165 WP_156862799.1 type I restriction endonuclease subunit R -
FKL89_RS11025 2435931..2436350 - 420 WP_156862800.1 MerR family transcriptional regulator -
FKL89_RS11030 2436322..2436639 - 318 WP_156862801.1 integration host factor subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(31-147)

Antitoxin

Vibrio phage ICP1, Orf50

(6-80)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17367.10 Da        Isoelectric Point: 9.6257

>T128132 WP_156862798.1 NZ_CP041352:2431990-2432475 [Casimicrobium huifangae]
VTLRFTAPEPLVAQHAVDAFDCGEPVLDDWLKRRALANQLSGASRTFVVLDDGARACGYYALAAGAVAHQAATGGVRRNM
PDPIPVLVLARLAVDRRAQGMQLGGALLQDALNRALVVSQNTGVRALLVHALHERARLFYAHYGFQPSPLDAMTLMLRLK
S

Download         Length: 486 bp

>T128132 NZ_CP041352:2431990-2432475 [Casimicrobium huifangae]
GTGACGCTGCGGTTCACGGCGCCGGAGCCACTGGTGGCCCAGCACGCGGTGGATGCGTTCGACTGTGGCGAGCCGGTGCT
CGATGACTGGCTGAAGCGCCGCGCCCTGGCCAACCAGTTGAGCGGCGCCAGCCGCACGTTCGTGGTGCTCGACGACGGCG
CGCGGGCGTGCGGCTATTACGCGCTGGCCGCCGGCGCCGTGGCGCACCAGGCGGCGACCGGCGGCGTGCGCCGCAACATG
CCGGACCCGATCCCCGTGCTGGTGCTGGCAAGGCTGGCAGTGGATCGCCGCGCACAGGGCATGCAGCTGGGCGGCGCCCT
GCTGCAAGACGCGCTGAACCGGGCGCTCGTGGTGTCGCAGAACACGGGGGTGCGGGCGCTGCTGGTGCACGCCCTGCACG
AGCGGGCGCGGCTGTTTTATGCACACTACGGCTTTCAGCCCTCACCGCTGGACGCCATGACGCTGATGCTGCGCCTGAAA
TCATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 9879.27 Da        Isoelectric Point: 4.9669

>AT128132 WP_156862797.1 NZ_CP041352:2431708-2431986 [Casimicrobium huifangae]
MRDAAINLRALPEQRDLIDHAAQLLGKNRSDFMLEAACDRAQAVLLDQVFFSLDAEKFRAFNAALDASAAPNAGLARLLA
VTPPWAPTTSAA

Download         Length: 279 bp

>AT128132 NZ_CP041352:2431708-2431986 [Casimicrobium huifangae]
ATGCGTGATGCCGCCATCAATTTGCGCGCCCTGCCGGAGCAGCGTGATCTGATCGATCACGCGGCGCAACTGCTGGGCAA
GAACCGTTCGGATTTCATGCTGGAAGCCGCGTGTGACCGGGCGCAGGCGGTGCTGCTGGACCAGGTGTTCTTCAGCCTCG
ATGCTGAGAAGTTTCGCGCCTTCAATGCCGCGCTGGACGCGTCCGCTGCCCCCAATGCCGGGCTGGCGCGGCTGCTGGCC
GTCACGCCGCCCTGGGCGCCGACCACCAGCGCAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References