Detailed information of TA system TA128132

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacT-ataR/DUF1778(antitoxin)
• Location: 2431708..2432475
• Replicon: chromosome
• Accession: NZ_CP041352
• Organism: Casimicrobium huifangae strain SJ-1

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: FKL89_RS11010
• Protein ID: WP_156862798.1
• Coordinates: 2431990..2432475 (+)
• Length: 162 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: FKL89_RS11005
• Protein ID: WP_156862797.1
• Coordinates: 2431708..2431986 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FKL89_RS10990	2427036..2428574	-	1539	WP_156862794.1	hypothetical protein	-
FKL89_RS10995	2428751..2430334	+	1584	WP_156862795.1	type I restriction-modification system subunit M	-
FKL89_RS11000	2430324..2431622	+	1299	WP_156862796.1	restriction endonuclease subunit S	-
FKL89_RS11005	2431708..2431986	+	279	WP_156862797.1	DUF1778 domain-containing protein	Antitoxin
FKL89_RS11010	2431990..2432475	+	486	WP_156862798.1	GNAT family N-acetyltransferase	Toxin
FKL89_RS11015	2432472..2435636	+	3165	WP_156862799.1	type I restriction endonuclease subunit R	-
FKL89_RS11025	2435931..2436350	-	420	WP_156862800.1	MerR family transcriptional regulator	-
FKL89_RS11030	2436322..2436639	-	318	WP_156862801.1	integration host factor subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (31-147)

Antitoxin

• Vibrio phage ICP1, Orf50 (6-80)

Sequences

Toxin

Protein

• Length: 162 a.a.
• Molecular weight: 17367.10 Da
• Isoelectric Point: 9.6257

>T128132 WP_156862798.1 NZ_CP041352:2431990-2432475 [Casimicrobium huifangae]
VTLRFTAPEPLVAQHAVDAFDCGEPVLDDWLKRRALANQLSGASRTFVVLDDGARACGYYALAAGAVAHQAATGGVRRNM
PDPIPVLVLARLAVDRRAQGMQLGGALLQDALNRALVVSQNTGVRALLVHALHERARLFYAHYGFQPSPLDAMTLMLRLK
S

Nucleotide

• Length: 486 bp

>T128132 NZ_CP041352:2431990-2432475 [Casimicrobium huifangae]
GTGACGCTGCGGTTCACGGCGCCGGAGCCACTGGTGGCCCAGCACGCGGTGGATGCGTTCGACTGTGGCGAGCCGGTGCT
CGATGACTGGCTGAAGCGCCGCGCCCTGGCCAACCAGTTGAGCGGCGCCAGCCGCACGTTCGTGGTGCTCGACGACGGCG
CGCGGGCGTGCGGCTATTACGCGCTGGCCGCCGGCGCCGTGGCGCACCAGGCGGCGACCGGCGGCGTGCGCCGCAACATG
CCGGACCCGATCCCCGTGCTGGTGCTGGCAAGGCTGGCAGTGGATCGCCGCGCACAGGGCATGCAGCTGGGCGGCGCCCT
GCTGCAAGACGCGCTGAACCGGGCGCTCGTGGTGTCGCAGAACACGGGGGTGCGGGCGCTGCTGGTGCACGCCCTGCACG
AGCGGGCGCGGCTGTTTTATGCACACTACGGCTTTCAGCCCTCACCGCTGGACGCCATGACGCTGATGCTGCGCCTGAAA
TCATGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 9879.27 Da
• Isoelectric Point: 4.9669

>AT128132 WP_156862797.1 NZ_CP041352:2431708-2431986 [Casimicrobium huifangae]
MRDAAINLRALPEQRDLIDHAAQLLGKNRSDFMLEAACDRAQAVLLDQVFFSLDAEKFRAFNAALDASAAPNAGLARLLA
VTPPWAPTTSAA

Nucleotide

• Length: 279 bp

>AT128132 NZ_CP041352:2431708-2431986 [Casimicrobium huifangae]
ATGCGTGATGCCGCCATCAATTTGCGCGCCCTGCCGGAGCAGCGTGATCTGATCGATCACGCGGCGCAACTGCTGGGCAA
GAACCGTTCGGATTTCATGCTGGAAGCCGCGTGTGACCGGGCGCAGGCGGTGCTGCTGGACCAGGTGTTCTTCAGCCTCG
ATGCTGAGAAGTTTCGCGCCTTCAATGCCGCGCTGGACGCGTCCGCTGCCCCCAATGCCGGGCTGGCGCGGCTGCTGGCC
GTCACGCCGCCCTGGGCGCCGACCACCAGCGCAGCCTGA