Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1721064..1721663 Replicon chromosome
Accession NZ_CP041352
Organism Casimicrobium huifangae strain SJ-1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FKL89_RS07920 Protein ID WP_156862246.1
Coordinates 1721373..1721663 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FKL89_RS07915 Protein ID WP_156862245.1
Coordinates 1721064..1721363 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FKL89_RS07900 1716806..1718044 - 1239 WP_156862242.1 MFS transporter -
FKL89_RS07905 1718192..1720033 + 1842 WP_156862243.1 DNA helicase RecQ -
FKL89_RS07910 1720142..1721050 - 909 WP_156862244.1 hypothetical protein -
FKL89_RS07915 1721064..1721363 - 300 WP_156862245.1 putative addiction module antidote protein Antitoxin
FKL89_RS07920 1721373..1721663 - 291 WP_156862246.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FKL89_RS07925 1721800..1722495 - 696 WP_156862247.1 aspartate/glutamate racemase family protein -
FKL89_RS07930 1722690..1723877 - 1188 WP_156862248.1 fumarylacetoacetate hydrolase family protein -
FKL89_RS07935 1723912..1725432 - 1521 WP_156862249.1 CoA-acylating methylmalonate-semialdehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-91)

Antitoxin

Uncharacterized protein HI1420

(5-95)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10990.64 Da        Isoelectric Point: 10.4973

>T128130 WP_156862246.1 NZ_CP041352:c1721663-1721373 [Casimicrobium huifangae]
MIEVRQTETYVEWFASLRDRQVRARIDIRIRRLSLGNPGDVKAVGEGVSELRIDYGPGYRVYFVRRGQTVVILLAGGDKR
TQDRDIKTALELARIA

Download         Length: 291 bp

>T128130 NZ_CP041352:c1721663-1721373 [Casimicrobium huifangae]
ATGATCGAAGTCCGGCAAACTGAGACCTATGTGGAGTGGTTTGCGTCACTCAGAGATCGGCAAGTGCGGGCACGAATCGA
CATCCGCATTCGCCGCCTGTCGTTGGGCAATCCCGGCGATGTGAAGGCTGTCGGCGAAGGCGTGTCCGAACTTCGCATCG
ACTATGGTCCGGGTTACCGTGTTTACTTTGTCCGGCGCGGACAAACCGTTGTGATCCTGCTTGCGGGCGGCGACAAGCGG
ACACAGGATCGTGACATCAAGACCGCCCTTGAACTGGCCCGCATCGCTTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10560.01 Da        Isoelectric Point: 4.6364

>AT128130 WP_156862245.1 NZ_CP041352:c1721363-1721064 [Casimicrobium huifangae]
MASTLKTHPWDPAEHLETEDDIAAYLEAAFEEGDPSLIAAALGDIARAKGMAQIARDTGLGRESLYKALSLEGNPEFATI
MKVVSALGLKLHATAIQPR

Download         Length: 300 bp

>AT128130 NZ_CP041352:c1721363-1721064 [Casimicrobium huifangae]
ATGGCAAGCACATTGAAAACCCATCCGTGGGATCCTGCGGAGCACCTTGAGACCGAGGACGATATCGCCGCATATCTTGA
GGCTGCATTCGAGGAAGGTGATCCGTCGCTCATCGCTGCCGCGCTCGGCGACATTGCCCGCGCAAAGGGCATGGCGCAAA
TCGCACGCGATACCGGGCTCGGGCGCGAGAGCCTTTACAAGGCCCTGTCCTTAGAAGGCAATCCGGAGTTTGCGACGATC
ATGAAGGTGGTCAGCGCGCTGGGGCTTAAGTTGCACGCAACTGCAATCCAACCCCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References