Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 176992..177545 Replicon chromosome
Accession NZ_CP041352
Organism Casimicrobium huifangae strain SJ-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FKL89_RS00840 Protein ID WP_156860853.1
Coordinates 177252..177545 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FKL89_RS00835 Protein ID WP_156860852.1
Coordinates 176992..177264 (+) Length 91 a.a.

Genomic Context

FKL89_RS00835FKL89_RS00840FKL89_RS20245FKL89_RS00850FKL89_RS00815FKL89_RS00820FKL89_RS00825FKL89_RS00830FKL89_RS00855FKL89_RS00860
Location: 176992..177264 (273 bp)
Type: Antitoxin
Protein ID: WP_156860852.1
Location: 177252..177545 (294 bp)
Type: Toxin
Protein ID: WP_156860853.1
Location: 177545..177880 (336 bp)
Type: Others
Protein ID: Protein_167
Location: 178378..180219 (1842 bp)
Type: Others
Protein ID: WP_156864499.1
Location: 172090..172407 (318 bp)
Type: Others
Protein ID: WP_033990572.1
Location: 172493..173119 (627 bp)
Type: Others
Protein ID: WP_106685585.1
Location: 173231..176257 (3027 bp)
Type: Others
Protein ID: WP_156860851.1
Location: 176254..176823 (570 bp)
Type: Others
Protein ID: WP_156864497.1
Location: 180317..181330 (1014 bp)
Type: Others
Protein ID: WP_022580065.1
Location: 181398..182120 (723 bp)
Type: Others
Protein ID: WP_033990568.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FKL89_RS00815172090..172407-318WP_033990572.1type II toxin-antitoxin system PrlF family antitoxin-
FKL89_RS00820172493..173119-627WP_106685585.1integrase-
FKL89_RS00825173231..176257-3027WP_156860851.1Tn3 family transposase-
FKL89_RS00830176254..176823-570WP_156864497.1recombinase family protein-
FKL89_RS00835176992..177264+273WP_156860852.1CopG family ribbon-helix-helix proteinAntitoxin
FKL89_RS00840177252..177545+294WP_156860853.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FKL89_RS20245177545..177880+336Protein_167transposase-
FKL89_RS00850178378..180219+1842WP_156864499.1TraI domain-containing protein-
FKL89_RS00855180317..181330-1014WP_022580065.1DUF4917 family protein-
FKL89_RS00860181398..182120-723WP_033990568.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--148468..342798194330
-flankIS/Tn--176254..176823569


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10799.33 Da        Isoelectric Point: 5.1583

>T128128 WP_156860853.1 NZ_CP041352:177252-177545 [Casimicrobium huifangae]
VPQVIVTEGAAEGLERCRKFLATKAPDAARRAGQAIERQFLLLETAPDIGRPFPEMPELRELVIAFGDSGYVALYRHEPD
ADAVYILAFRHQKEAGY

Download         Length: 294 bp

>T128128 NZ_CP041352:177252-177545 [Casimicrobium huifangae]
GTGCCACAAGTAATCGTCACCGAGGGCGCAGCCGAAGGCCTGGAGCGATGCCGGAAGTTCCTGGCCACCAAGGCCCCGGA
TGCCGCCAGGCGAGCCGGTCAGGCCATCGAACGGCAATTCCTGCTGCTGGAAACGGCTCCCGACATTGGCCGCCCGTTCC
CTGAAATGCCGGAGTTGCGTGAACTGGTTATTGCCTTCGGGGATTCCGGCTATGTAGCCCTGTACCGCCATGAACCTGAC
GCCGATGCGGTCTACATCCTGGCATTCCGGCATCAGAAAGAAGCGGGCTACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10571.84 Da        Isoelectric Point: 6.9793

>AT128128 WP_156860852.1 NZ_CP041352:176992-177264 [Casimicrobium huifangae]
MATSLKIDETLKGRVHHLAGQRRRSPHWIMLEAIQQYVEREEARESFKQEALASWAAYQETGRHLTGQEVRTWLNTWGTE
DERAVPECHK

Download         Length: 273 bp

>AT128128 NZ_CP041352:176992-177264 [Casimicrobium huifangae]
ATGGCAACATCACTCAAAATTGACGAGACGCTGAAAGGCCGCGTCCACCACCTCGCCGGCCAGCGCCGTCGCTCGCCGCA
CTGGATCATGCTGGAAGCCATTCAGCAATACGTCGAGCGCGAGGAAGCCCGCGAGAGCTTCAAGCAGGAAGCCTTGGCTT
CCTGGGCTGCCTATCAGGAAACCGGTCGGCACCTGACTGGCCAGGAAGTGCGCACTTGGTTGAACACCTGGGGCACCGAA
GACGAAAGGGCGGTGCCTGAGTGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References