Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2172223..2172491 Replicon chromosome
Accession NZ_CP041304
Organism Escherichia coli strain MSHS 133

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2172351..2172453 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2172223..2172491 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FK544_RS11585 2168776..2169438 - 663 WP_000944256.1 exodeoxyribonuclease X -
FK544_RS11590 2169462..2170118 - 657 WP_000011673.1 carbon-nitrogen hydrolase family protein -
FK544_RS11595 2170220..2170450 - 231 WP_000916759.1 DNA polymerase III subunit theta -
FK544_RS11600 2170589..2170963 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FK544_RS11605 2170967..2171839 + 873 WP_141841220.1 copper homeostasis membrane protein CopD -
FK544_RS11610 2171852..2172193 + 342 WP_000976472.1 YebY family protein -
- 2172223..2172491 - 269 - - Antitoxin
- 2172351..2172453 + 103 - - Toxin
FK544_RS11615 2172588..2173244 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
FK544_RS11620 2173245..2173436 - 192 WP_001317886.1 YebW family protein -
FK544_RS11625 2173541..2173777 - 237 WP_001295499.1 DUF1480 family protein -
FK544_RS11630 2173895..2175334 - 1440 WP_001317885.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T128024 NZ_CP041304:2172351-2172453 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT128024 NZ_CP041304:c2172491-2172223 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References