Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2062997..2063268 Replicon chromosome
Accession NZ_CP041302
Organism Escherichia coli strain MSHS 472

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2063127..2063230 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2062997..2063268 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FK543_RS11010 2059552..2060214 - 663 WP_000944256.1 exodeoxyribonuclease X -
FK543_RS11015 2060238..2060894 - 657 WP_141874711.1 carbon-nitrogen hydrolase family protein -
FK543_RS11020 2060996..2061226 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FK543_RS11025 2061365..2061739 + 375 WP_000204699.1 CopC domain-containing protein YobA -
FK543_RS11030 2061743..2062615 + 873 Protein_1938 copper homeostasis membrane protein CopD -
FK543_RS11035 2062628..2062969 + 342 WP_000976492.1 YebY family protein -
- 2062997..2063268 - 272 - - Antitoxin
- 2063127..2063230 + 104 - - Toxin
FK543_RS11040 2063365..2064021 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
FK543_RS11045 2064022..2064213 - 192 WP_001296140.1 YebW family protein -
FK543_RS11050 2064318..2064554 - 237 WP_001295499.1 DUF1480 family protein -
FK543_RS11055 2064672..2066111 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T127983 NZ_CP041302:2063127-2063230 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT127983 NZ_CP041302:c2063268-2062997 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References