Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2232130..2232401 Replicon chromosome
Accession NZ_CP041300
Organism Escherichia coli O1:H42 strain CLSC36

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2232260..2232363 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2232130..2232401 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FK541_RS11695 2228685..2229347 - 663 WP_000944256.1 exodeoxyribonuclease X -
FK541_RS11700 2229371..2230027 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
FK541_RS11705 2230129..2230359 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FK541_RS11710 2230498..2230872 + 375 WP_022645803.1 CopC domain-containing protein YobA -
FK541_RS11715 2230876..2231748 + 873 WP_022645802.1 copper homeostasis membrane protein CopD -
FK541_RS11720 2231761..2232102 + 342 WP_000976472.1 YebY family protein -
- 2232130..2232401 - 272 - - Antitoxin
- 2232260..2232363 + 104 - - Toxin
FK541_RS11725 2232498..2233154 + 657 WP_022645801.1 protein-serine/threonine phosphatase -
FK541_RS11730 2233155..2233346 - 192 WP_001296140.1 YebW family protein -
FK541_RS11735 2233451..2233687 - 237 WP_001295499.1 DUF1480 family protein -
FK541_RS11740 2233805..2235244 - 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T127955 NZ_CP041300:2232260-2232363 [Escherichia coli O1:H42]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT127955 NZ_CP041300:c2232401-2232130 [Escherichia coli O1:H42]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References