Detailed information of TA system TA127934

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): NpoTA/ParE(toxin)
• Location: 3071946..3073061
• Replicon: chromosome
• Accession: NZ_CP041291
• Organism: Acinetobacter indicus strain 94-2

Toxin (Protein)

• Gene name: NpoT
• Uniprot ID: -
• Locus tag: FK537_RS15125
• Protein ID: WP_104483720.1
• Coordinates: 3071946..3072110 (-)
• Length: 55 a.a.

Antitoxin (Protein)

• Gene name: NpoA
• Uniprot ID: -
• Locus tag: FK537_RS15130
• Protein ID: WP_075166616.1
• Coordinates: 3072192..3073061 (-)
• Length: 290 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FK537_RS15110	3067924..3068946	+	1023	WP_075166613.1	ferredoxin reductase	-
FK537_RS15115	3068970..3070127	+	1158	WP_171293522.1	fatty acid desaturase	-
FK537_RS15120	3070428..3071846	+	1419	WP_081410039.1	iron-containing redox enzyme family protein	-
FK537_RS15125	3071946..3072110	-	165	WP_104483720.1	hypothetical protein	Toxin
FK537_RS15130	3072192..3073061	-	870	WP_075166616.1	SDR family oxidoreductase	Antitoxin
FK537_RS15135	3073164..3073403	-	240	WP_075166617.1	DUF2171 domain-containing protein	-
FK537_RS15140	3074062..3075303	+	1242	WP_075166618.1	MFS transporter	-
FK537_RS15145	3075741..3076151	+	411	WP_075166619.1	KGG domain-containing protein	-
FK537_RS15150	3076198..3077265	-	1068	WP_168369713.1	transposase	-
FK537_RS15155	3077532..3077981	-	450	WP_005178047.1	cyanase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 55 a.a.
• Molecular weight: 6194.81 Da
• Isoelectric Point: 10.1466

>T127934 WP_104483720.1 NZ_CP041291:c3072110-3071946 [Acinetobacter indicus]
MSRGDKSAYTDKQKRQARHIIESEKERGHSEEEAERIGWSIVNKQDGGGKKKSH

Nucleotide

• Length: 165 bp

>T127934 NZ_CP041291:c3072110-3071946 [Acinetobacter indicus]
ATGTCTAGAGGTGATAAGTCGGCCTATACCGACAAGCAGAAACGTCAGGCCCGCCATATTATTGAATCGGAAAAAGAGCG
AGGCCATTCCGAAGAAGAAGCAGAACGCATTGGCTGGTCTATCGTCAATAAACAGGATGGCGGCGGTAAAAAGAAATCTC
ACTAA

Antitoxin

Protein

• Length: 290 a.a.
• Molecular weight: 31891.98 Da
• Isoelectric Point: 4.8531

>AT127934 WP_075166616.1 NZ_CP041291:c3073061-3072192 [Acinetobacter indicus]
MNHYPDSPSPQEKQEHQPGVQYKMTPEPEIIKSNYQGSQKLKDKVALITGGDSGIGRSVAVLFAREGANIIIPYLEEDQD
AQDTKRLVEQEGRQCLLIQCDLRQHAAVQQMVDLALQQFPHINILVNNAAVQYPQKTIEDINPEQLHKTFETNLYPLFYV
TQLLIPQMQPGDSIINTTSITSYQGHNELIDYASTKGAITAFTRSLSTNLLKNKTGIRVNGVAPGPIWTPLIPSSFDEEQ
LKGFGEDTPMGRMGQPSEVAPAYLFLASDEASYISGQVIHVNGGTVVNG

Nucleotide

• Length: 870 bp

>AT127934 NZ_CP041291:c3073061-3072192 [Acinetobacter indicus]
ATGAATCATTATCCTGACAGCCCATCTCCGCAAGAGAAGCAGGAGCATCAGCCCGGTGTGCAATATAAAATGACGCCCGA
ACCTGAAATTATTAAAAGCAATTATCAGGGTAGTCAAAAACTCAAAGACAAGGTGGCCTTAATTACCGGCGGTGATAGCG
GCATCGGCCGCTCCGTGGCAGTGCTGTTTGCCCGCGAAGGTGCCAATATTATTATTCCCTATTTAGAAGAAGATCAGGAT
GCGCAAGACACCAAGCGACTGGTTGAGCAGGAAGGTCGTCAATGTCTGCTGATTCAGTGTGACCTGCGCCAACATGCGGC
AGTACAGCAGATGGTCGATCTGGCTTTGCAGCAGTTTCCGCATATTAATATTCTGGTCAATAATGCCGCCGTACAATATC
CACAAAAAACCATTGAGGATATTAATCCCGAACAGCTGCATAAAACCTTTGAAACCAACCTCTACCCGCTGTTTTATGTG
ACCCAGTTACTCATTCCTCAAATGCAGCCCGGTGACAGTATTATCAATACCACCAGTATCACCAGCTATCAGGGCCATAA
TGAGCTCATTGATTATGCCAGTACCAAAGGGGCTATTACTGCCTTTACCCGTAGCCTATCGACCAACCTGCTAAAAAATA
AAACCGGGATTCGGGTGAATGGTGTCGCACCCGGCCCAATCTGGACACCATTAATTCCAAGCAGTTTTGATGAAGAACAG
CTAAAAGGTTTTGGTGAAGATACCCCCATGGGCCGCATGGGTCAGCCAAGTGAAGTTGCGCCGGCTTATCTGTTTTTAGC
CTCCGATGAAGCCAGCTATATTTCCGGTCAGGTGATTCATGTTAATGGCGGTACTGTTGTCAATGGTTAA