Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018760..2019031 Replicon chromosome
Accession NZ_CP041284
Organism Escherichia coli strain 54

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018890..2018993 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018760..2019031 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FK536_RS09735 2015315..2015977 - 663 WP_000944258.1 exodeoxyribonuclease X -
FK536_RS09740 2016001..2016657 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FK536_RS09745 2016759..2016989 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FK536_RS09750 2017128..2017502 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FK536_RS09755 2017506..2018378 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
FK536_RS09760 2018391..2018732 + 342 WP_000976472.1 YebY family protein -
- 2018760..2019031 - 272 - - Antitoxin
- 2018890..2018993 + 104 - - Toxin
FK536_RS09765 2019128..2019784 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
FK536_RS09770 2019785..2019976 - 192 WP_001338167.1 YebW family protein -
FK536_RS09775 2020081..2020317 - 237 WP_001338166.1 DUF1480 family protein -
FK536_RS09780 2020435..2021874 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T127918 NZ_CP041284:2018890-2018993 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT127918 NZ_CP041284:c2019031-2018760 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References