Detailed information of TA system TA127876

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 793822..794479
• Replicon: chromosome
• Accession: NZ_CP041247
• Organism: Raoultella electrica strain DSM 102253

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: Electrica_RS03845
• Protein ID: WP_100684294.1
• Coordinates: 794069..794479 (+)
• Length: 137 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A514ELX1
• Locus tag: Electrica_RS03840
• Protein ID: WP_004867358.1
• Coordinates: 793822..794088 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Electrica_RS03815	788962..790395	-	1434	WP_141963514.1	6-phospho-beta-glucosidase	-
Electrica_RS03820	790515..791243	-	729	WP_131048725.1	MurR/RpiR family transcriptional regulator	-
Electrica_RS03825	791293..791604	+	312	WP_131048603.1	N(4)-acetylcytidine aminohydrolase	-
Electrica_RS03830	791766..792425	+	660	WP_131048604.1	hemolysin III family protein	-
Electrica_RS03835	792541..793524	-	984	WP_141963516.1	tRNA-modifying protein YgfZ	-
Electrica_RS03840	793822..794088	+	267	WP_004867358.1	FAD assembly factor SdhE	Antitoxin
Electrica_RS03845	794069..794479	+	411	WP_100684294.1	protein YgfX	Toxin
Electrica_RS03850	794485..795006	-	522	WP_100684295.1	flavodoxin FldB	-
Electrica_RS03855	795184..796080	+	897	WP_100684392.1	site-specific tyrosine recombinase XerD	-
Electrica_RS03860	796103..796816	+	714	WP_141963518.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-
Electrica_RS03865	796822..798555	+	1734	WP_141963520.1	single-stranded-DNA-specific exonuclease RecJ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (3-132)

Antitoxin

• Flavinator of succinate dehydrogenase (7-79)

Sequences

Toxin

Protein

• Length: 137 a.a.
• Molecular weight: 16212.09 Da
• Isoelectric Point: 11.5202

>T127876 WP_100684294.1 NZ_CP041247:794069-794479 [Raoultella electrica]
VVLWQSDLRISWRSQWFSLLLHGVVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWVAADSMDAREWRDLRRLVLQKPAQD

Nucleotide

• Length: 411 bp

>T127876 NZ_CP041247:794069-794479 [Raoultella electrica]
GTGGTCCTGTGGCAATCTGATTTACGCATTTCCTGGCGTTCACAGTGGTTCTCGTTGCTGCTACATGGCGTTGTGGCGGC
TATTGTGCTGCTGATGCCGTGGCCGCTGAGCTACACACCGCTTTGGCTACTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TGCGCAGCCAGCGGCGGATCCACGCCTGCCGGGGGGAAATAAAGCTGATGACCGATTCGCGTTTGCGTTGGCAAAAAGCG
GAATGGGAGATTGTCGGCACGCCGTGGGTGATTAATAGCGGGATGTTGCTGCGCCTGCAGGATATGCAAACGCGCCGCCG
TCAGCATCTGTGGGTCGCTGCAGACAGTATGGATGCCAGAGAGTGGCGAGATCTGCGCCGGTTGGTGTTACAAAAACCGG
CACAGGATTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10553.05 Da
• Isoelectric Point: 4.8432

>AT127876 WP_004867358.1 NZ_CP041247:793822-794088 [Raoultella electrica]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI

Nucleotide

• Length: 267 bp

>AT127876 NZ_CP041247:793822-794088 [Raoultella electrica]
ATGGACATTACGAATAAAGCCCGCATCCACTGGGCATGCCGCCGGGGTATGCGTGAACTTGATATCTCCATCATGCCGTT
TTTCGAGTATGAGTACGATACGCTCAGCGATGAAGACAAACAGCTGTTCATCCGCCTGTTAGAAAACGACGATCCGGATC
TGTTTAACTGGCTGATGAATCATGGCGAACCGGCTGATGCGCAACTGCAACGGATGGTAAAATTAATCCAGACTCGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Structures

Antitoxin

• AlphaFold DB: A0A514ELX1