Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 693172..693725 Replicon chromosome
Accession NZ_CP041247
Organism Raoultella electrica strain DSM 102253

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag Electrica_RS03370 Protein ID WP_100683472.1
Coordinates 693411..693725 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag Electrica_RS03365 Protein ID WP_100683473.1
Coordinates 693172..693408 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Electrica_RS03340 688624..689202 + 579 WP_141963425.1 TetR/AcrR family transcriptional regulator -
Electrica_RS03345 689203..690297 - 1095 WP_141963427.1 iron-containing redox enzyme family protein -
Electrica_RS03350 690508..691410 + 903 WP_141963429.1 DMT family transporter -
Electrica_RS03355 691452..692609 + 1158 WP_141963431.1 MFS transporter -
Electrica_RS03360 692858..692992 - 135 WP_142255833.1 transposase -
Electrica_RS03365 693172..693408 + 237 WP_100683473.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
Electrica_RS03370 693411..693725 + 315 WP_100683472.1 CcdB family protein Toxin
Electrica_RS03375 693877..694272 + 396 Protein_654 aconitate hydratase B -
Electrica_RS03380 694511..695173 - 663 Protein_655 IS630 family transposase -
Electrica_RS03385 695381..697327 - 1947 WP_141963433.1 AIPR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11475.29 Da        Isoelectric Point: 6.4489

>T127874 WP_100683472.1 NZ_CP041247:693411-693725 [Raoultella electrica]
MQFTVYANTGKSTVYPLLLDVTSDIIGQLNRRIVIPLLPVDRYPAGHRPDRLVPFVSLTDGREYAVMTHELASIPVQALG
AVFCDAAQYRSQVKAAIDFLIDGI

Download         Length: 315 bp

>T127874 NZ_CP041247:693411-693725 [Raoultella electrica]
ATGCAATTCACCGTATATGCGAATACTGGTAAAAGCACCGTTTACCCTCTGCTGCTCGATGTCACCAGCGATATTATTGG
ACAACTGAACCGCCGGATAGTGATCCCGCTGCTGCCGGTTGACAGGTATCCGGCAGGCCACCGCCCGGATCGCCTTGTTC
CCTTCGTCAGTCTGACAGACGGCAGAGAATACGCGGTAATGACCCACGAGCTGGCAAGTATCCCGGTTCAGGCGCTGGGG
GCGGTGTTCTGCGATGCTGCGCAGTACCGTTCGCAGGTAAAGGCTGCAATTGATTTTCTCATTGACGGCATTTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8929.94 Da        Isoelectric Point: 6.4798

>AT127874 WP_100683473.1 NZ_CP041247:693172-693408 [Raoultella electrica]
MAAKQRSTQSVTMTVERALLARAREAGINLSATLTAALDAELRHHEAKKWQEENREAIEALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp

>AT127874 NZ_CP041247:693172-693408 [Raoultella electrica]
ATGGCAGCGAAACAACGCAGCACACAGAGCGTGACCATGACGGTGGAACGCGCCTTACTGGCCCGGGCGCGTGAGGCAGG
CATTAACCTGAGTGCGACCCTGACAGCCGCGTTAGATGCCGAGCTTCGGCACCATGAAGCGAAAAAATGGCAGGAAGAGA
ACAGGGAAGCCATTGAAGCACTAAATCGTTTCCATGATGAGCATGGCTGTTTCAGCGATGAATACAGGACATTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References