Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 2796248..2796762 Replicon chromosome
Accession NZ_CP041243
Organism Brevundimonas sp. M20

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FKQ52_RS13765 Protein ID WP_141627708.1
Coordinates 2796502..2796762 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FKQ52_RS13760 Protein ID WP_141627707.1
Coordinates 2796248..2796505 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FKQ52_RS13735 2791311..2791517 + 207 WP_141627702.1 helix-turn-helix domain-containing protein -
FKQ52_RS16490 2791576..2791737 + 162 WP_168196866.1 hypothetical protein -
FKQ52_RS13740 2792036..2792458 + 423 WP_141627703.1 DoxX family protein -
FKQ52_RS13745 2792651..2793136 + 486 WP_141627704.1 MerR family DNA-binding transcriptional regulator -
FKQ52_RS13750 2793139..2794923 + 1785 WP_141627705.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
FKQ52_RS13755 2795046..2796209 + 1164 WP_141627706.1 acyl-CoA dehydrogenase family protein -
FKQ52_RS13760 2796248..2796505 + 258 WP_141627707.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FKQ52_RS13765 2796502..2796762 + 261 WP_141627708.1 Txe/YoeB family addiction module toxin Toxin
FKQ52_RS13770 2796759..2797478 + 720 WP_141627709.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
FKQ52_RS13775 2797672..2799033 + 1362 WP_141627710.1 glutamate--cysteine ligase -
FKQ52_RS13780 2799036..2799542 + 507 WP_141627711.1 hypothetical protein -
FKQ52_RS13785 2799645..2801204 + 1560 WP_141627712.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10355.87 Da        Isoelectric Point: 9.0289

>T127873 WP_141627708.1 NZ_CP041243:2796502-2796762 [Brevundimonas sp. M20]
MKLTFQAHGWEDYLHWQETDRKMLRKLNGLIKECLRTPFEGTGKPEPLKGALAGWWSRRLDQEYRLVYRATDEGLLIAQC
RYHYDR

Download         Length: 261 bp

>T127873 NZ_CP041243:2796502-2796762 [Brevundimonas sp. M20]
ATGAAGCTGACCTTCCAGGCCCATGGCTGGGAGGATTACCTTCACTGGCAGGAGACCGACCGGAAGATGCTGCGCAAGCT
CAACGGTCTGATCAAGGAATGCCTGCGCACGCCGTTCGAGGGGACTGGAAAGCCTGAACCGCTCAAGGGCGCGTTGGCCG
GCTGGTGGTCACGACGCCTCGATCAGGAGTATCGTCTGGTCTATCGCGCGACCGATGAGGGCTTGCTCATCGCCCAGTGC
CGGTACCATTACGACCGATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9360.49 Da        Isoelectric Point: 4.2213

>AT127873 WP_141627707.1 NZ_CP041243:2796248-2796505 [Brevundimonas sp. M20]
MNAISITELRKNLAAAVDRVTQDHDYTIITRDGGKPAAVLMSLEDFTSWQETEYLLRSPANAARLLESIAELDAGGGQVR
ELIEE

Download         Length: 258 bp

>AT127873 NZ_CP041243:2796248-2796505 [Brevundimonas sp. M20]
ATGAACGCGATCTCGATCACCGAACTGCGCAAGAACCTCGCGGCCGCCGTGGACCGCGTGACGCAGGACCACGACTACAC
GATCATCACCCGGGACGGCGGCAAACCCGCCGCTGTCCTGATGTCTCTCGAGGACTTCACGTCCTGGCAGGAGACCGAAT
ACCTGCTCCGCAGCCCTGCCAATGCCGCGCGGCTGCTGGAGTCGATCGCTGAGCTGGACGCGGGCGGCGGGCAGGTTCGC
GAGTTGATCGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References