Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1984699..1985342 Replicon chromosome
Accession NZ_CP041243
Organism Brevundimonas sp. M20

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FKQ52_RS09615 Protein ID WP_141626982.1
Coordinates 1984699..1985091 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FKQ52_RS09620 Protein ID WP_141626983.1
Coordinates 1985088..1985342 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FKQ52_RS09595 1980150..1980749 + 600 WP_141626978.1 hypothetical protein -
FKQ52_RS09600 1980824..1983145 + 2322 WP_141626979.1 NAD-dependent DNA ligase LigA -
FKQ52_RS09605 1983167..1983589 + 423 WP_141626980.1 DUF2147 domain-containing protein -
FKQ52_RS09610 1983635..1984624 - 990 WP_141626981.1 aldo/keto reductase -
FKQ52_RS09615 1984699..1985091 - 393 WP_141626982.1 type II toxin-antitoxin system VapC family toxin Toxin
FKQ52_RS09620 1985088..1985342 - 255 WP_141626983.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FKQ52_RS09625 1985377..1987188 - 1812 WP_141626984.1 aminopeptidase P family protein -
FKQ52_RS09630 1987222..1987671 - 450 WP_141626985.1 hypothetical protein -
FKQ52_RS09635 1987728..1988597 - 870 WP_141626986.1 50S ribosomal protein L11 methyltransferase -
FKQ52_RS16445 1988692..1989276 + 585 WP_168196823.1 hypothetical protein -
FKQ52_RS09645 1989346..1989555 - 210 WP_092310331.1 DUF3126 family protein -
FKQ52_RS09650 1989634..1990086 - 453 WP_141626987.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(2-63)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14207.23 Da        Isoelectric Point: 5.2327

>T127872 WP_141626982.1 NZ_CP041243:c1985091-1984699 [Brevundimonas sp. M20]
VIVDSSALIAIIFGEPEGTALLERLMFGSPRMSAATYFESGMVIDRKAKDDFAAKAFDRLLELTRVEVVAVTREHAEIAR
SAYREFGKGNHPASLNFGDCFAYALAKQAGEPLLFKGDDFARTDITSALK

Download         Length: 393 bp

>T127872 NZ_CP041243:c1985091-1984699 [Brevundimonas sp. M20]
GTGATCGTCGACAGTTCGGCCCTGATCGCCATTATATTTGGCGAGCCGGAAGGCACGGCGCTGCTCGAGCGGCTGATGTT
CGGATCACCACGTATGTCTGCGGCGACCTATTTCGAGAGCGGCATGGTCATTGATCGCAAGGCGAAAGATGACTTTGCAG
CCAAGGCTTTCGACCGATTGCTGGAGTTGACGAGGGTGGAAGTCGTGGCTGTTACCCGCGAGCACGCCGAAATTGCGCGC
AGCGCCTATCGCGAGTTCGGCAAGGGCAACCATCCGGCGTCGCTGAATTTCGGCGACTGTTTCGCCTATGCCCTCGCTAA
ACAGGCCGGCGAGCCGCTGTTGTTCAAAGGCGATGACTTCGCGCGGACAGACATCACTTCGGCCTTGAAATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9283.61 Da        Isoelectric Point: 5.1601

>AT127872 WP_141626983.1 NZ_CP041243:c1985342-1985088 [Brevundimonas sp. M20]
MLNIKNPETHRLARELAARRGETLTTAVTVALREQLAREPAEPPKAAAEEVMALIREMQAHLKPLEPGEDPTGFLYDPET
GRPA

Download         Length: 255 bp

>AT127872 NZ_CP041243:c1985342-1985088 [Brevundimonas sp. M20]
ATGCTGAACATCAAGAACCCCGAGACCCATAGACTGGCGCGCGAGCTGGCTGCGCGACGGGGGGAAACCCTGACCACGGC
GGTCACCGTCGCCCTGCGCGAACAGTTGGCGCGTGAACCGGCCGAGCCGCCCAAGGCGGCCGCCGAAGAGGTCATGGCGC
TGATCCGGGAGATGCAGGCGCACCTGAAGCCGCTTGAGCCCGGTGAAGATCCGACGGGCTTCCTGTATGACCCGGAGACG
GGACGTCCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References