Detailed information of TA system TA127871

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 97705..98457
• Replicon: chromosome
• Accession: NZ_CP041242
• Organism: Lysobacter alkalisoli strain SJ-36

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: FKV23_RS00480
• Protein ID: WP_141622098.1
• Coordinates: 97705..98181 (-)
• Length: 159 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: FKV23_RS00485
• Protein ID: WP_167284853.1
• Coordinates: 98185..98457 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FKV23_RS00460	92738..93658	-	921	WP_141622094.1	transcriptional regulator GcvA	-
FKV23_RS00465	93792..94616	+	825	WP_167284851.1	MBL fold metallo-hydrolase	-
FKV23_RS00470	94613..95479	+	867	WP_141622096.1	MBL fold metallo-hydrolase	-
FKV23_RS00475	95822..97537	+	1716	WP_141622097.1	cellulase family glycosylhydrolase	-
FKV23_RS00480	97705..98181	-	477	WP_141622098.1	GNAT family N-acetyltransferase	Toxin
FKV23_RS00485	98185..98457	-	273	WP_167284853.1	DUF1778 domain-containing protein	Antitoxin
FKV23_RS00490	98589..100592	-	2004	WP_141622100.1	exodeoxyribonuclease V subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (44-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (9-83)

Sequences

Toxin

Protein

• Length: 159 a.a.
• Molecular weight: 17274.92 Da
• Isoelectric Point: 7.0825

>T127871 WP_141622098.1 NZ_CP041242:c98181-97705 [Lysobacter alkalisoli]
MPLSAPSPLNDEHRLDDFRCSAPELTKWLLERARQNQASGASRCFVVCDEQQHVVGYYALAAGAVSHGDVPGRIRRNMPS
PIPVIVLGRLAVHADWVGQGIGQGLLKDAVQRTLQTCEQIGARALLCHAIDEEAKAFYLKHGFIVSPIHDMTVMLPLG

Nucleotide

• Length: 477 bp

>T127871 NZ_CP041242:c98181-97705 [Lysobacter alkalisoli]
TTGCCGCTCAGTGCCCCCAGCCCGCTCAACGATGAGCACCGGCTGGACGACTTCCGCTGCAGCGCACCGGAACTGACAAA
GTGGCTGTTGGAGCGGGCGCGCCAGAATCAGGCGTCTGGCGCATCGAGGTGTTTCGTCGTCTGTGACGAGCAGCAGCACG
TCGTGGGCTACTACGCGCTGGCGGCCGGCGCGGTGTCACATGGAGATGTGCCCGGCCGCATCCGACGCAACATGCCTAGT
CCGATCCCGGTCATCGTGTTGGGGCGCTTGGCTGTGCACGCGGACTGGGTTGGCCAAGGGATCGGACAGGGGTTGCTCAA
GGATGCCGTACAACGGACGTTGCAGACCTGCGAACAGATAGGCGCCCGTGCGCTGCTGTGCCACGCCATCGATGAAGAAG
CGAAGGCGTTCTACCTCAAACACGGCTTCATCGTGTCACCCATCCACGACATGACGGTGATGCTGCCACTCGGGTAA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9979.39 Da
• Isoelectric Point: 8.0290

>AT127871 WP_167284853.1 NZ_CP041242:c98457-98185 [Lysobacter alkalisoli]
MSAATSKVINFRAPAAKQALIDHAVEVSGMNRTEFILDAVCDKAREVLADQTRFALSRQALQRFNAQLDAPLEDNAAIRR
LLSTPAPWER

Nucleotide

• Length: 273 bp

>AT127871 NZ_CP041242:c98457-98185 [Lysobacter alkalisoli]
ATGAGCGCCGCCACCAGCAAGGTCATCAATTTCCGCGCGCCTGCCGCCAAGCAGGCGCTGATCGACCATGCCGTGGAAGT
CAGCGGCATGAACCGCACGGAGTTCATCCTGGACGCCGTGTGCGATAAGGCGCGAGAAGTGTTGGCCGACCAAACCCGGT
TCGCCCTGAGCCGGCAGGCCCTGCAGCGCTTCAATGCCCAGCTCGATGCGCCCCTGGAGGACAATGCGGCGATCCGCCGC
CTGTTGAGCACCCCGGCGCCCTGGGAGCGCTGA