Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1339181..1339821 Replicon plasmid pEmeITTGR7c
Accession NZ_CP041241
Organism Ensifer mexicanus strain ITTG R7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FKV68_RS30340 Protein ID WP_180942607.1
Coordinates 1339435..1339821 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FKV68_RS30335 Protein ID WP_180942606.1
Coordinates 1339181..1339435 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FKV68_RS30320 1335819..1336748 - 930 WP_180942603.1 SMP-30/gluconolactonase/LRE family protein -
FKV68_RS30325 1336757..1337104 - 348 WP_180942604.1 hypothetical protein -
FKV68_RS30330 1337162..1338190 - 1029 WP_180942605.1 extracellular solute-binding protein -
FKV68_RS30335 1339181..1339435 + 255 WP_180942606.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FKV68_RS30340 1339435..1339821 + 387 WP_180942607.1 type II toxin-antitoxin system VapC family toxin Toxin
FKV68_RS30345 1340413..1340975 + 563 Protein_1229 hypothetical protein -
FKV68_RS30350 1341296..1341514 + 219 Protein_1230 transposase -
FKV68_RS30355 1341501..1341692 + 192 Protein_1231 hypothetical protein -
FKV68_RS30360 1342704..1343762 - 1059 WP_180942608.1 L-idonate 5-dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA / katB 1..1933675 1933675


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14008.84 Da        Isoelectric Point: 4.6069

>T127869 WP_180942607.1 NZ_CP041241:1339435-1339821 [Ensifer mexicanus]
MVIDTSAIVAIAFNEPEAETYEQKVVDAPRRFISAATVLELAIVIESRLGEAGAAELDLWLYKAGVEIVAVDAEQIAVAR
RAWRSYGKGRHPAGLNYGDCFSYALARTRNEPLLYKGDDFSRTDIGTA

Download         Length: 387 bp

>T127869 NZ_CP041241:1339435-1339821 [Ensifer mexicanus]
ATGGTCATCGACACGTCCGCCATCGTCGCGATCGCATTCAACGAGCCGGAAGCAGAAACCTACGAACAAAAAGTCGTCGA
CGCTCCGCGGCGCTTCATCTCGGCCGCGACGGTCCTTGAACTCGCCATCGTCATCGAATCGCGCCTCGGCGAGGCAGGTG
CGGCAGAGCTTGATCTGTGGCTTTACAAGGCGGGTGTCGAAATCGTCGCCGTCGACGCGGAACAGATCGCCGTCGCAAGG
CGAGCCTGGCGCAGCTACGGCAAGGGCCGACATCCGGCCGGTCTGAACTATGGGGACTGTTTCTCCTATGCGCTGGCGAG
GACGCGCAACGAACCGCTGCTCTATAAAGGCGATGATTTCTCGCGAACAGATATAGGGACGGCATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9500.78 Da        Isoelectric Point: 5.9007

>AT127869 WP_180942606.1 NZ_CP041241:1339181-1339435 [Ensifer mexicanus]
MALSIKDLETERLAKALAEKTGETITMATRRALEERLRRLANAENRDVLLEELAASRRRWAKLPVHDNRSADEILGYDEN
GLPG

Download         Length: 255 bp

>AT127869 NZ_CP041241:1339181-1339435 [Ensifer mexicanus]
ATGGCGCTCAGCATTAAAGATCTAGAGACGGAACGTCTCGCCAAGGCGCTGGCCGAGAAAACTGGTGAAACCATCACCAT
GGCGACCCGCCGGGCACTGGAAGAACGGCTACGGCGCCTCGCAAACGCGGAAAATCGCGATGTTCTTCTCGAGGAGCTTG
CCGCCAGCCGCAGACGTTGGGCAAAGCTGCCGGTTCACGACAACCGCTCCGCCGATGAGATTTTGGGGTACGACGAAAAT
GGGCTCCCCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References