Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 245854..246379 Replicon chromosome
Accession NZ_CP041235
Organism Sulfurimonas sp. S2-6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FJR45_RS01375 Protein ID WP_193151023.1
Coordinates 246095..246379 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FJR45_RS01370 Protein ID WP_193151022.1
Coordinates 245854..246111 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJR45_RS01345 240875..242215 - 1341 WP_193151020.1 hypothetical protein -
FJR45_RS01350 242478..243941 - 1464 WP_193151021.1 sulfate adenylyltransferase subunit CysN -
FJR45_RS01355 243943..244854 - 912 WP_193151004.1 sulfate adenylyltransferase subunit CysD -
FJR45_RS01360 244858..245295 - 438 WP_193151005.1 hypothetical protein -
FJR45_RS01365 245292..245576 - 285 WP_193151006.1 nucleotidyltransferase domain-containing protein -
FJR45_RS01370 245854..246111 + 258 WP_193151022.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FJR45_RS01375 246095..246379 + 285 WP_193151023.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FJR45_RS01380 246491..246754 - 264 WP_193151024.1 BrnA antitoxin family protein -
FJR45_RS01385 246723..246962 - 240 WP_193151869.1 BrnT family toxin -
FJR45_RS01390 247128..247889 - 762 WP_193151025.1 sulfotransferase family 2 domain-containing protein -
FJR45_RS01395 247858..248553 - 696 WP_193151026.1 NAD(P)-dependent oxidoreductase -
FJR45_RS01400 248550..249581 - 1032 WP_193151027.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-68)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11295.07 Da        Isoelectric Point: 10.1892

>T127859 WP_193151023.1 NZ_CP041235:246095-246379 [Sulfurimonas sp. S2-6]
MIYYLDFHPKALKEWSRLDYATKQQFHKKLKNKLSNPRVPKDRLSGYANVYKIKLRNAGYRLAYEVKDDEIVVFVISIGK
RENNEIYDNLKDRI

Download         Length: 285 bp

>T127859 NZ_CP041235:246095-246379 [Sulfurimonas sp. S2-6]
ATGATTTATTATCTTGATTTTCATCCAAAAGCTTTGAAGGAGTGGAGTAGGTTGGATTATGCCACAAAACAACAATTCCA
CAAAAAACTCAAAAATAAATTGTCCAATCCAAGAGTACCAAAAGACAGACTTAGCGGATATGCAAATGTATATAAAATAA
AACTTAGAAATGCTGGATATAGATTGGCTTATGAGGTTAAAGATGACGAGATTGTGGTGTTTGTGATCAGTATAGGAAAG
AGAGAAAACAATGAAATTTATGATAATTTAAAAGATAGAATTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9532.77 Da        Isoelectric Point: 4.0061

>AT127859 WP_193151022.1 NZ_CP041235:245854-246111 [Sulfurimonas sp. S2-6]
MQPMLANYTASITELKQSPTQLLKDAGNEAIAILNHNVASAYLVPSDLYAKMIDIIDDYYLTQAVEERYNDGEKPIRVDI
DDLLS

Download         Length: 258 bp

>AT127859 NZ_CP041235:245854-246111 [Sulfurimonas sp. S2-6]
ATGCAGCCAATGTTAGCAAATTATACAGCAAGTATTACAGAACTGAAGCAATCACCAACTCAGTTGCTGAAGGATGCAGG
AAACGAGGCAATAGCGATACTCAATCACAATGTTGCCAGTGCCTATCTGGTACCCAGCGATCTCTATGCCAAAATGATAG
ATATTATCGATGATTATTATCTGACACAAGCGGTAGAAGAGAGATATAATGATGGAGAAAAACCGATCAGAGTAGATATT
GATGATTTATTATCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References