Detailed information of TA system TA127857

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 129485..130001
• Replicon: chromosome
• Accession: NZ_CP041235
• Organism: Sulfurimonas sp. S2-6

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FJR45_RS00685
• Protein ID: WP_193150908.1
• Coordinates: 129485..129766 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FJR45_RS00690
• Protein ID: WP_193151861.1
• Coordinates: 129747..130001 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FJR45_RS00640	124593..124820	+	228	WP_193150902.1	ribbon-helix-helix protein, CopG family	-
FJR45_RS00645	124820..125071	+	252	WP_193150903.1	type II toxin-antitoxin system RelE/ParE family toxin	-
FJR45_RS00650	125219..125380	-	162	WP_193151859.1	IS3 family transposase	-
FJR45_RS00655	125428..126177	-	750	WP_193151860.1	IS3 family transposase	-
FJR45_RS00660	126135..126467	-	333	WP_193150904.1	transposase	-
FJR45_RS00665	126556..127080	+	525	WP_193150905.1	hypothetical protein	-
FJR45_RS00670	127205..127435	+	231	WP_193150906.1	ribbon-helix-helix protein, CopG family	-
FJR45_RS00675	127428..127679	+	252	WP_193150907.1	type II toxin-antitoxin system RelE/ParE family toxin	-
FJR45_RS00680	127854..129225	-	1372	Protein_134	transposase	-
FJR45_RS00685	129485..129766	+	282	WP_193150908.1	BrnT family toxin	Toxin
FJR45_RS00690	129747..130001	+	255	WP_193151861.1	CopG family transcriptional regulator	Antitoxin
FJR45_RS00695	130047..130289	+	243	WP_193150909.1	DUF2442 domain-containing protein	-
FJR45_RS00700	130642..130752	+	111	WP_193150910.1	excalibur calcium-binding domain-containing protein	-
FJR45_RS00705	130794..131594	-	801	WP_193150911.1	phosphotransferase	-
FJR45_RS00710	131595..132020	-	426	WP_193150912.1	hypothetical protein	-
FJR45_RS00715	132086..132763	+	678	WP_193150913.1	energy-coupling factor ABC transporter permease	-
FJR45_RS00720	132778..133614	-	837	WP_193150914.1	sirohydrochlorin cobaltochelatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-81)

Antitoxin

• CopG antitoxin (8-71)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11100.63 Da
• Isoelectric Point: 6.9531

>T127857 WP_193150908.1 NZ_CP041235:129485-129766 [Sulfurimonas sp. S2-6]
VKFEYDENKSQINKQKHGIDFVEAQKLWQDEDALVIPANIVDNEIRYALISKILTECFVVIFTIRDDINRIISVRRCRKN
EEKNYEKNNSQRV

Nucleotide

• Length: 282 bp

>T127857 NZ_CP041235:129485-129766 [Sulfurimonas sp. S2-6]
GTGAAATTTGAGTATGATGAAAATAAAAGTCAAATCAATAAACAAAAGCATGGAATAGATTTTGTCGAAGCACAAAAACT
TTGGCAGGACGAAGATGCACTTGTAATTCCTGCAAATATTGTTGATAATGAAATTCGCTATGCTCTCATCTCAAAAATAC
TCACTGAATGCTTTGTTGTTATATTTACTATTAGAGATGATATAAACAGAATTATAAGTGTCCGTAGATGTAGAAAAAAT
GAGGAGAAAAATTATGAAAAAAATAACAGCCAAAGAGTTTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9743.09 Da
• Isoelectric Point: 5.2072

>AT127857 WP_193151861.1 NZ_CP041235:129747-130001 [Sulfurimonas sp. S2-6]
ITAKEFDEKFDNGEDISEYLDFSKATRPNALKTDTKKVNVDFPQWVIESLDKEAKKIGVTRQSIIKVWIAERLKEEIGNF
PKIQ

Nucleotide

• Length: 255 bp

>AT127857 NZ_CP041235:129747-130001 [Sulfurimonas sp. S2-6]
ATAACAGCCAAAGAGTTTGATGAAAAATTTGACAATGGTGAAGATATAAGTGAGTATCTTGATTTTTCAAAAGCGACAAG
ACCAAATGCTCTCAAAACAGATACTAAAAAAGTAAATGTTGATTTTCCACAATGGGTTATAGAATCCTTAGACAAAGAAG
CAAAGAAAATCGGTGTTACAAGACAGTCTATCATTAAAGTTTGGATAGCTGAAAGACTTAAAGAAGAGATTGGAAACTTT
CCAAAAATACAATAA