Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 3450218..3450755 Replicon chromosome
Accession NZ_CP041203
Organism Cellulomonas sp. Y8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FKM96_RS15615 Protein ID WP_147796011.1
Coordinates 3450495..3450755 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FKM96_RS15610 Protein ID WP_147796010.1
Coordinates 3450218..3450490 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FKM96_RS15590 3445402..3446961 + 1560 WP_210417461.1 citramalate synthase -
FKM96_RS15595 3447066..3448226 + 1161 WP_147796007.1 glycerate kinase -
FKM96_RS15600 3448266..3449138 + 873 WP_147796008.1 sensor domain-containing protein -
FKM96_RS15605 3449213..3450091 + 879 WP_147796009.1 NAD(P)-dependent oxidoreductase -
FKM96_RS15610 3450218..3450490 + 273 WP_147796010.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FKM96_RS15615 3450495..3450755 + 261 WP_147796011.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FKM96_RS15620 3450976..3451785 + 810 WP_147796012.1 23S ribosomal RNA methyltransferase Erm -
FKM96_RS15625 3451796..3452871 + 1076 Protein_3094 lipoate--protein ligase family protein -
FKM96_RS15630 3452971..3453369 + 399 WP_147796013.1 YccF domain-containing protein -
FKM96_RS15635 3453391..3453774 - 384 WP_147796014.1 DUF202 domain-containing protein -
FKM96_RS15640 3453771..3454142 - 372 WP_147796015.1 DUF202 domain-containing protein -
FKM96_RS15645 3454139..3454912 - 774 WP_147796016.1 YggS family pyridoxal phosphate-dependent enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9789.41 Da        Isoelectric Point: 11.5223

>T127782 WP_147796011.1 NZ_CP041203:3450495-3450755 [Cellulomonas sp. Y8]
VYEVRFAPPAVRAVDRLPPKLADAVLRFCRERLAENPQRFTKPLTGRLAGERSGYVGIGFRVIVRVDEESRQVHVLRMGP
RAGVYR

Download         Length: 261 bp

>T127782 NZ_CP041203:3450495-3450755 [Cellulomonas sp. Y8]
GTGTACGAGGTCCGGTTCGCCCCGCCGGCCGTCCGCGCGGTCGACCGGCTGCCTCCGAAGCTGGCGGACGCCGTGCTGCG
GTTCTGCCGGGAGCGGCTCGCGGAGAATCCCCAGCGGTTCACCAAGCCGCTGACCGGTCGGCTCGCCGGCGAGCGGAGCG
GCTACGTCGGCATCGGGTTCCGCGTGATCGTCCGGGTGGACGAGGAGAGCCGGCAGGTGCACGTGCTGCGGATGGGGCCC
CGCGCGGGCGTCTACCGCTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9721.93 Da        Isoelectric Point: 4.4047

>AT127782 WP_147796010.1 NZ_CP041203:3450218-3450490 [Cellulomonas sp. Y8]
MRMLPLNEAKTNLSAVLDEVQSSHEPVTITRHGKPAGVLVSADDMDTLLETLAWLSDRDHAAEMAEADAAVAAGETLGLD
EVEARLARRR

Download         Length: 273 bp

>AT127782 NZ_CP041203:3450218-3450490 [Cellulomonas sp. Y8]
ATGCGGATGCTTCCCCTGAACGAGGCGAAGACCAACCTCTCCGCCGTGCTGGACGAGGTGCAGTCCTCGCACGAGCCCGT
GACGATCACGCGGCACGGGAAGCCGGCGGGCGTGCTGGTCTCGGCCGACGACATGGACACGCTGCTCGAGACGCTCGCGT
GGCTGTCCGACCGCGACCACGCCGCCGAGATGGCCGAGGCCGACGCCGCGGTCGCGGCGGGCGAGACGCTGGGTCTCGAC
GAGGTCGAGGCGCGGCTGGCCCGGCGACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References