Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/HTH_31(antitoxin)
Location 4780881..4782125 Replicon chromosome
Accession NZ_CP041191
Organism Labrenzia sp. PHM005

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FJ695_RS21625 Protein ID WP_141187371.1
Coordinates 4781502..4782125 (+) Length 208 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FJ695_RS21620 Protein ID WP_141187370.1
Coordinates 4780881..4781453 (+) Length 191 a.a.

Genomic Context

FJ695_RS21610FJ695_RS21615FJ695_RS21620FJ695_RS21625FJ695_RS21630FJ695_RS21645FJ695_RS21595FJ695_RS21600FJ695_RS21605FJ695_RS21635FJ695_RS21640
Location: 4779216..4779842 (627 bp)
Type: Others
Protein ID: WP_168206450.1
Location: 4780463..4780831 (369 bp)
Type: Others
Protein ID: WP_168206552.1
Location: 4780881..4781453 (573 bp)
Type: Antitoxin
Protein ID: WP_141187370.1
Location: 4781502..4782125 (624 bp)
Type: Toxin
Protein ID: WP_141187371.1
Location: 4782242..4782622 (381 bp)
Type: Others
Protein ID: WP_141187372.1
Location: 4785004..4785465 (462 bp)
Type: Others
Protein ID: WP_141187375.1
Location: 4775921..4776769 (849 bp)
Type: Others
Protein ID: WP_141187366.1
Location: 4777023..4777949 (927 bp)
Type: Others
Protein ID: WP_209010766.1
Location: 4777997..4778830 (834 bp)
Type: Others
Protein ID: WP_141187368.1
Location: 4782606..4783400 (795 bp)
Type: Others
Protein ID: WP_141187373.1
Location: 4783418..4784899 (1482 bp)
Type: Others
Protein ID: WP_141187374.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FJ695_RS215954775921..4776769-849WP_141187366.1phosphonate ABC transporter, permease protein PhnE-
FJ695_RS216004777023..4777949-927WP_209010766.1phosphonate ABC transporter substrate-binding protein-
FJ695_RS216054777997..4778830-834WP_141187368.1phosphonate ABC transporter ATP-binding protein-
FJ695_RS216104779216..4779842+627WP_168206450.1chloramphenicol acetyltransferase-
FJ695_RS216154780463..4780831+369WP_168206552.1VOC family protein-
FJ695_RS216204780881..4781453+573WP_141187370.1helix-turn-helix domain-containing proteinAntitoxin
FJ695_RS216254781502..4782125+624WP_141187371.1HD domain-containing proteinToxin
FJ695_RS216304782242..4782622+381WP_141187372.1STAS/SEC14 domain-containing protein-
FJ695_RS216354782606..4783400-795WP_141187373.1class II glutamine amidotransferase-
FJ695_RS216404783418..4784899-1482WP_141187374.1aminotransferase class V-fold PLP-dependent enzyme-
FJ695_RS216454785004..4785465+462WP_141187375.1Lrp/AsnC family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(28-159)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-51)


Sequences

Toxin        


Download         Length: 208 a.a.        Molecular weight: 23282.50 Da        Isoelectric Point: 4.7005

>T127772 WP_141187371.1 NZ_CP041191:4781502-4782125 [Labrenzia sp. PHM005]
MTSEPKKSPAPAMDATRLAGLLAFLQEAERLKDTLRSGTTRQNRPESTAEHSWRLCLMVLLFERELADIDMLRLLKLCVI
HDLGEAISGDVPAPFQTPDDDREAVERRDFVDLCRPLPDDLKAELLGLFDEYSAAETAEAKLAKGFDKLETILQHHLMPS
ADAEFHTFNLGYGLERTNALPLTGQIRDVVDQQTRQIINRLTQVKAD

Download         Length: 624 bp

>T127772 NZ_CP041191:4781502-4782125 [Labrenzia sp. PHM005]
ATGACATCTGAGCCAAAAAAATCCCCTGCTCCAGCGATGGACGCTACCCGGCTGGCTGGTCTGCTTGCCTTTTTGCAAGA
AGCCGAGCGGCTGAAGGATACGCTTCGATCCGGAACCACCCGGCAGAACCGGCCAGAAAGCACTGCCGAGCACAGTTGGC
GCCTCTGCTTGATGGTTCTGCTGTTTGAACGCGAGCTTGCGGACATCGATATGCTGAGGCTTCTAAAGCTGTGTGTGATC
CACGATCTGGGTGAGGCGATTTCCGGTGATGTGCCGGCTCCCTTTCAAACTCCCGACGATGACCGCGAAGCGGTCGAGCG
CCGGGATTTCGTGGATCTGTGCAGACCTCTACCGGATGACTTGAAGGCTGAGTTGCTGGGTCTCTTTGATGAGTATTCTG
CGGCAGAAACAGCAGAGGCAAAGCTCGCCAAAGGTTTCGACAAGCTGGAGACCATTCTGCAGCATCATCTGATGCCTAGT
GCCGACGCGGAATTTCACACCTTTAATCTCGGCTACGGTTTGGAGCGGACTAACGCCCTCCCGCTCACCGGGCAGATCCG
TGATGTGGTGGACCAGCAAACCCGCCAGATCATCAACCGGCTTACGCAGGTAAAGGCTGATTGA

Antitoxin


Download         Length: 191 a.a.        Molecular weight: 21541.77 Da        Isoelectric Point: 9.8206

>AT127772 WP_141187370.1 NZ_CP041191:4780881-4781453 [Labrenzia sp. PHM005]
MSVAIIPLAKNLGPSLRRWRVINRVKQQALAEELKVSQSKISRWENGTSEPESPELRRLLNLLEARPETAADRALQALVM
QSSHPVHLVCDLTHRLLAASPKRTRDWHIPLSDLMHKPLWRFASGGIRDAEDTLGDNGWYEPLGPDIVFDTERADFAEMT
IPKSRIRITRLPLSDGRFVRLVRDDVTVAA

Download         Length: 573 bp

>AT127772 NZ_CP041191:4780881-4781453 [Labrenzia sp. PHM005]
ATGTCCGTTGCAATCATCCCCCTTGCCAAAAACCTTGGGCCCTCCTTGCGCCGCTGGCGGGTGATCAATCGTGTCAAACA
GCAGGCACTGGCAGAGGAACTGAAGGTTTCACAATCGAAGATTTCCAGATGGGAAAACGGCACTTCAGAGCCGGAAAGTC
CGGAGTTGCGGAGACTTTTAAACTTGCTCGAAGCCCGGCCGGAGACGGCTGCAGACCGGGCGCTGCAGGCTCTGGTCATG
CAGTCGTCTCACCCGGTGCATCTGGTTTGTGATCTGACCCACCGGCTGCTGGCAGCGTCCCCAAAAAGAACACGCGACTG
GCACATACCGCTGTCTGACTTGATGCATAAGCCCCTCTGGCGTTTTGCCTCTGGCGGCATCCGGGACGCGGAAGACACTC
TCGGCGACAACGGCTGGTACGAGCCGCTCGGGCCGGACATTGTCTTTGACACCGAACGGGCTGATTTTGCCGAAATGACC
ATTCCGAAAAGCCGGATCCGGATTACCCGTTTGCCGCTGTCAGACGGCCGGTTTGTGCGCCTAGTGCGCGATGACGTGAC
AGTTGCTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References