Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/HTH_31(antitoxin)
Location 4780881..4782125 Replicon chromosome
Accession NZ_CP041191
Organism Labrenzia sp. PHM005

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FJ695_RS21625 Protein ID WP_141187371.1
Coordinates 4781502..4782125 (+) Length 208 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FJ695_RS21620 Protein ID WP_141187370.1
Coordinates 4780881..4781453 (+) Length 191 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJ695_RS21595 4775921..4776769 - 849 WP_141187366.1 phosphonate ABC transporter, permease protein PhnE -
FJ695_RS21600 4777023..4777949 - 927 WP_209010766.1 phosphonate ABC transporter substrate-binding protein -
FJ695_RS21605 4777997..4778830 - 834 WP_141187368.1 phosphonate ABC transporter ATP-binding protein -
FJ695_RS21610 4779216..4779842 + 627 WP_168206450.1 chloramphenicol acetyltransferase -
FJ695_RS21615 4780463..4780831 + 369 WP_168206552.1 VOC family protein -
FJ695_RS21620 4780881..4781453 + 573 WP_141187370.1 helix-turn-helix domain-containing protein Antitoxin
FJ695_RS21625 4781502..4782125 + 624 WP_141187371.1 HD domain-containing protein Toxin
FJ695_RS21630 4782242..4782622 + 381 WP_141187372.1 STAS/SEC14 domain-containing protein -
FJ695_RS21635 4782606..4783400 - 795 WP_141187373.1 class II glutamine amidotransferase -
FJ695_RS21640 4783418..4784899 - 1482 WP_141187374.1 aminotransferase class V-fold PLP-dependent enzyme -
FJ695_RS21645 4785004..4785465 + 462 WP_141187375.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(28-159)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-51)


Sequences

Toxin        


Download         Length: 208 a.a.        Molecular weight: 23282.50 Da        Isoelectric Point: 4.7005

>T127772 WP_141187371.1 NZ_CP041191:4781502-4782125 [Labrenzia sp. PHM005]
MTSEPKKSPAPAMDATRLAGLLAFLQEAERLKDTLRSGTTRQNRPESTAEHSWRLCLMVLLFERELADIDMLRLLKLCVI
HDLGEAISGDVPAPFQTPDDDREAVERRDFVDLCRPLPDDLKAELLGLFDEYSAAETAEAKLAKGFDKLETILQHHLMPS
ADAEFHTFNLGYGLERTNALPLTGQIRDVVDQQTRQIINRLTQVKAD

Download         Length: 624 bp

>T127772 NZ_CP041191:4781502-4782125 [Labrenzia sp. PHM005]
ATGACATCTGAGCCAAAAAAATCCCCTGCTCCAGCGATGGACGCTACCCGGCTGGCTGGTCTGCTTGCCTTTTTGCAAGA
AGCCGAGCGGCTGAAGGATACGCTTCGATCCGGAACCACCCGGCAGAACCGGCCAGAAAGCACTGCCGAGCACAGTTGGC
GCCTCTGCTTGATGGTTCTGCTGTTTGAACGCGAGCTTGCGGACATCGATATGCTGAGGCTTCTAAAGCTGTGTGTGATC
CACGATCTGGGTGAGGCGATTTCCGGTGATGTGCCGGCTCCCTTTCAAACTCCCGACGATGACCGCGAAGCGGTCGAGCG
CCGGGATTTCGTGGATCTGTGCAGACCTCTACCGGATGACTTGAAGGCTGAGTTGCTGGGTCTCTTTGATGAGTATTCTG
CGGCAGAAACAGCAGAGGCAAAGCTCGCCAAAGGTTTCGACAAGCTGGAGACCATTCTGCAGCATCATCTGATGCCTAGT
GCCGACGCGGAATTTCACACCTTTAATCTCGGCTACGGTTTGGAGCGGACTAACGCCCTCCCGCTCACCGGGCAGATCCG
TGATGTGGTGGACCAGCAAACCCGCCAGATCATCAACCGGCTTACGCAGGTAAAGGCTGATTGA

Antitoxin


Download         Length: 191 a.a.        Molecular weight: 21541.77 Da        Isoelectric Point: 9.8206

>AT127772 WP_141187370.1 NZ_CP041191:4780881-4781453 [Labrenzia sp. PHM005]
MSVAIIPLAKNLGPSLRRWRVINRVKQQALAEELKVSQSKISRWENGTSEPESPELRRLLNLLEARPETAADRALQALVM
QSSHPVHLVCDLTHRLLAASPKRTRDWHIPLSDLMHKPLWRFASGGIRDAEDTLGDNGWYEPLGPDIVFDTERADFAEMT
IPKSRIRITRLPLSDGRFVRLVRDDVTVAA

Download         Length: 573 bp

>AT127772 NZ_CP041191:4780881-4781453 [Labrenzia sp. PHM005]
ATGTCCGTTGCAATCATCCCCCTTGCCAAAAACCTTGGGCCCTCCTTGCGCCGCTGGCGGGTGATCAATCGTGTCAAACA
GCAGGCACTGGCAGAGGAACTGAAGGTTTCACAATCGAAGATTTCCAGATGGGAAAACGGCACTTCAGAGCCGGAAAGTC
CGGAGTTGCGGAGACTTTTAAACTTGCTCGAAGCCCGGCCGGAGACGGCTGCAGACCGGGCGCTGCAGGCTCTGGTCATG
CAGTCGTCTCACCCGGTGCATCTGGTTTGTGATCTGACCCACCGGCTGCTGGCAGCGTCCCCAAAAAGAACACGCGACTG
GCACATACCGCTGTCTGACTTGATGCATAAGCCCCTCTGGCGTTTTGCCTCTGGCGGCATCCGGGACGCGGAAGACACTC
TCGGCGACAACGGCTGGTACGAGCCGCTCGGGCCGGACATTGTCTTTGACACCGAACGGGCTGATTTTGCCGAAATGACC
ATTCCGAAAAGCCGGATCCGGATTACCCGTTTGCCGCTGTCAGACGGCCGGTTTGTGCGCCTAGTGCGCGATGACGTGAC
AGTTGCTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References