Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 4899172..4899685 Replicon chromosome
Accession NZ_CP041189
Organism Pseudomonas sp. NIBRBAC000502773

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NIBR502773_RS22595 Protein ID WP_141156984.1
Coordinates 4899172..4899456 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1C1WCL4
Locus tag NIBR502773_RS22600 Protein ID WP_065928241.1
Coordinates 4899446..4899685 (-) Length 80 a.a.

Genomic Context

NIBR502773_RS22575NIBR502773_RS22580NIBR502773_RS22590NIBR502773_RS22605NIBR502773_RS22610NIBR502773_RS22615NIBR502773_RS22625NIBR502773_RS22585NIBR502773_RS22595NIBR502773_RS22600NIBR502773_RS22620NIBR502773_RS22630NIBR502773_RS22635NIBR502773_RS22640NIBR502773_RS22645
Location: 4895357..4896298 (942 bp)
Type: Others
Protein ID: WP_141156980.1
Location: 4896358..4897689 (1332 bp)
Type: Others
Protein ID: WP_141156981.1
Location: 4898247..4899164 (918 bp)
Type: Others
Protein ID: WP_141156983.1
Location: 4899785..4900195 (411 bp)
Type: Others
Protein ID: WP_141156985.1
Location: 4900250..4900891 (642 bp)
Type: Others
Protein ID: WP_141156986.1
Location: 4901010..4901537 (528 bp)
Type: Others
Protein ID: WP_027604356.1
Location: 4902196..4902978 (783 bp)
Type: Others
Protein ID: WP_141156987.1
Location: 4897690..4898178 (489 bp)
Type: Others
Protein ID: WP_141156982.1
Location: 4899172..4899456 (285 bp)
Type: Toxin
Protein ID: WP_141156984.1
Location: 4899446..4899685 (240 bp)
Type: Antitoxin
Protein ID: WP_065928241.1
Location: 4901592..4902017 (426 bp)
Type: Others
Protein ID: WP_027604355.1
Location: 4902979..4903479 (501 bp)
Type: Others
Protein ID: WP_141156988.1
Location: 4903573..4903914 (342 bp)
Type: Others
Protein ID: WP_141156989.1
Location: 4904003..4904413 (411 bp)
Type: Others
Protein ID: WP_027604351.1
Location: 4904436..4904618 (183 bp)
Type: Others
Protein ID: WP_003189411.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NIBR502773_RS225754895357..4896298+942WP_141156980.1hydroxymethylglutaryl-CoA lyase-
NIBR502773_RS225804896358..4897689+1332WP_141156981.1MFS transporter-
NIBR502773_RS225854897690..4898178-489WP_141156982.1DMT family transporter-
NIBR502773_RS225904898247..4899164+918WP_141156983.1LysR family transcriptional regulator-
NIBR502773_RS225954899172..4899456-285WP_141156984.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NIBR502773_RS226004899446..4899685-240WP_065928241.1ribbon-helix-helix protein, CopG familyAntitoxin
NIBR502773_RS226054899785..4900195+411WP_141156985.1fosfomycin resistance glutathione transferase-
NIBR502773_RS226104900250..4900891+642WP_141156986.1LysE family translocator-
NIBR502773_RS226154901010..4901537+528WP_027604356.1DUF4142 domain-containing protein-
NIBR502773_RS226204901592..4902017-426WP_027604355.1low affinity iron permease family protein-
NIBR502773_RS226254902196..4902978+783WP_141156987.1GNAT family N-acetyltransferase-
NIBR502773_RS226304902979..4903479-501WP_141156988.1methylated-DNA--[protein]-cysteine S-methyltransferase-
NIBR502773_RS226354903573..4903914-342WP_141156989.1hypothetical protein-
NIBR502773_RS226404904003..4904413-411WP_027604351.1type II toxin-antitoxin system HicB family antitoxin-
NIBR502773_RS226454904436..4904618-183WP_003189411.1type II toxin-antitoxin system HicA family toxin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10970.65 Da        Isoelectric Point: 10.0872

>T127767 WP_141156984.1 NZ_CP041189:c4899456-4899172 [Pseudomonas sp. NIBRBAC000502773]
MQVEWLRTALKNLDDEAAYIAQENPKAAHEFVQAIMVGLGHVAEFPAVGKEGRVPGTREWVVPRWPYIVPYRIRDGRLQV
MRFFHTRRQPPTSW

Download         Length: 285 bp

>T127767 NZ_CP041189:c4899456-4899172 [Pseudomonas sp. NIBRBAC000502773]
ATGCAGGTTGAGTGGCTGAGGACAGCCCTCAAGAACCTTGATGATGAAGCCGCGTACATTGCGCAGGAAAATCCCAAAGC
CGCCCATGAGTTCGTCCAGGCCATCATGGTTGGGCTAGGACATGTCGCTGAATTTCCTGCTGTGGGAAAGGAAGGTCGAG
TGCCAGGAACGCGGGAGTGGGTAGTGCCTCGATGGCCTTACATCGTTCCCTACCGGATTCGAGATGGACGATTACAAGTG
ATGCGATTTTTTCATACACGTCGCCAGCCACCGACATCCTGGTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8582.79 Da        Isoelectric Point: 5.0958

>AT127767 WP_065928241.1 NZ_CP041189:c4899685-4899446 [Pseudomonas sp. NIBRBAC000502773]
MSVMSLRIPEDIAATLASLAKATGRSKSFLAVDALREYLTREAWQIEEIQKALKEADAGEFATAAEVKAVADKWRTNAG

Download         Length: 240 bp

>AT127767 NZ_CP041189:c4899685-4899446 [Pseudomonas sp. NIBRBAC000502773]
ATGTCTGTTATGTCCCTACGCATACCCGAAGACATCGCCGCCACGCTTGCCAGTCTCGCCAAGGCGACCGGGCGCAGCAA
ATCCTTTCTCGCAGTCGATGCATTACGCGAATACTTGACGCGCGAAGCGTGGCAAATCGAAGAAATTCAAAAAGCATTGA
AAGAAGCAGACGCAGGCGAGTTCGCAACGGCTGCGGAGGTAAAAGCCGTCGCCGATAAATGGCGCACCAATGCAGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1C1WCL4

References