Detailed information of TA system TA127765

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 610823..611388
• Replicon: chromosome
• Accession: NZ_CP041188
• Organism: Pseudarthrobacter sp. NIBRBAC000502772

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: NIBR502772_RS02855
• Protein ID: WP_210412435.1
• Coordinates: 611134..611388 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: NIBR502772_RS02850
• Protein ID: WP_141138990.1
• Coordinates: 610823..611098 (+)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NIBR502772_RS02820	606062..607087	-	1026	WP_141138985.1	FUSC family protein	-
NIBR502772_RS02825	607526..607831	-	306	WP_141138986.1	hypothetical protein	-
NIBR502772_RS02830	607907..609082	-	1176	WP_141138987.1	NAD-dependent formate dehydrogenase	-
NIBR502772_RS02835	609207..610103	-	897	WP_210412378.1	LysR family transcriptional regulator	-
NIBR502772_RS02845	610505..610651	+	147	WP_141138989.1	DUF3892 domain-containing protein	-
NIBR502772_RS02850	610823..611098	+	276	WP_141138990.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
NIBR502772_RS02855	611134..611388	+	255	WP_210412435.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
NIBR502772_RS02860	611623..612327	-	705	WP_141138992.1	alpha/beta hydrolase	-
NIBR502772_RS02865	612337..613113	-	777	WP_141138993.1	ABC transporter ATP-binding protein	-
NIBR502772_RS02870	613148..614290	-	1143	WP_141138994.1	ABC transporter permease	-
NIBR502772_RS02875	614456..615805	+	1350	WP_141138995.1	sensor histidine kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (1-81)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9639.19 Da
• Isoelectric Point: 10.8700

>T127765 WP_210412435.1 NZ_CP041188:611134-611388 [Pseudarthrobacter sp. NIBRBAC000502772]
IEVTSPALKGFRRLPEKAAAAIVEFITGVLADNPRRLSKPLTNELLGLRTARRGDYRVLFTLDIEGHTLYVHRIEHRADV
YKRR

Nucleotide

• Length: 255 bp

>T127765 NZ_CP041188:611134-611388 [Pseudarthrobacter sp. NIBRBAC000502772]
ATCGAAGTCACCAGCCCTGCACTGAAGGGATTTCGTCGGCTGCCGGAGAAGGCCGCCGCCGCAATCGTCGAATTCATCAC
CGGTGTCCTGGCCGATAATCCCCGCCGGCTCAGCAAGCCCCTCACCAATGAACTCCTCGGCCTGCGCACGGCACGCCGAG
GTGACTACCGCGTGTTGTTCACCCTCGATATCGAAGGGCACACCTTATACGTCCATCGCATCGAACACCGTGCGGACGTC
TACAAGCGGCGTTAG

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 10197.36 Da
• Isoelectric Point: 4.7078

>AT127765 WP_141138990.1 NZ_CP041188:610823-611098 [Pseudarthrobacter sp. NIBRBAC000502772]
MRTVPLSEAKDKLSALVEEADKTHEIIQITRHGHPSAVLMSADDLESLQETVHWLSQPGIREDLDQARRDIAEGNTVSGD
DLRREFGLPPR

Nucleotide

• Length: 276 bp

>AT127765 NZ_CP041188:610823-611098 [Pseudarthrobacter sp. NIBRBAC000502772]
ATGAGAACGGTACCGCTCAGCGAAGCCAAGGACAAGCTTTCCGCGCTTGTAGAGGAAGCGGACAAGACGCATGAGATCAT
CCAGATCACGCGTCATGGGCACCCCTCGGCCGTGTTGATGTCCGCCGACGACCTGGAGTCCCTGCAGGAAACGGTCCACT
GGCTGTCGCAGCCTGGCATCCGCGAAGACCTGGACCAGGCGCGACGCGATATCGCCGAAGGCAACACGGTCAGCGGCGAT
GACCTGCGCCGTGAATTCGGACTGCCGCCGAGGTGA