Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 5171578..5172216 Replicon chromosome
Accession NZ_CP041185
Organism Janthinobacterium tructae strain SNU WT1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FJQ89_RS22760 Protein ID WP_141171809.1
Coordinates 5171794..5172216 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FJQ89_RS22755 Protein ID WP_141171808.1
Coordinates 5171578..5171787 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJQ89_RS22735 5167378..5168676 - 1299 WP_168208508.1 alpha/beta hydrolase -
FJQ89_RS22740 5168922..5170160 + 1239 WP_141171805.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -
FJQ89_RS22745 5170157..5171038 + 882 WP_141171806.1 ATP-binding protein -
FJQ89_RS22750 5171035..5171457 + 423 WP_141171807.1 NUDIX domain-containing protein -
FJQ89_RS22755 5171578..5171787 + 210 WP_141171808.1 DNA-binding protein Antitoxin
FJQ89_RS22760 5171794..5172216 + 423 WP_141171809.1 type II toxin-antitoxin system VapC family toxin Toxin
FJQ89_RS22765 5172230..5172421 - 192 WP_034748814.1 DNA gyrase inhibitor YacG -
FJQ89_RS22770 5172440..5173195 - 756 WP_141171810.1 cell division protein ZapD -
FJQ89_RS22775 5173279..5173905 - 627 WP_141171811.1 dephospho-CoA kinase -
FJQ89_RS22780 5173939..5174808 - 870 WP_141172945.1 A24 family peptidase -
FJQ89_RS22785 5174915..5176111 - 1197 WP_141171812.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14970.31 Da        Isoelectric Point: 5.5610

>T127764 WP_141171809.1 NZ_CP041185:5171794-5172216 [Janthinobacterium tructae]
MPMPGYLLDTDVIVAARKGGAAPAGVLAFFERVAPDARYVPVQVIAQLCAGIQRSWRREAALEALALEGWLEAVLAEYAP
RLLEFDLDCALVCARLHGHGHAHGVDGQIAAMGIAYGLTVVSGRLDSFVTQGLRLENPFS

Download         Length: 423 bp

>T127764 NZ_CP041185:5171794-5172216 [Janthinobacterium tructae]
ATGCCGATGCCTGGCTATCTGCTCGATACGGATGTGATCGTTGCGGCGCGCAAGGGCGGCGCTGCACCGGCAGGTGTGCT
CGCATTTTTCGAACGGGTAGCACCTGACGCGCGCTATGTGCCGGTACAGGTGATCGCGCAGTTGTGTGCGGGCATACAGC
GCAGCTGGCGGCGCGAAGCGGCGCTGGAAGCACTGGCGCTGGAAGGCTGGCTGGAAGCCGTGCTGGCAGAGTATGCGCCG
CGGCTGCTGGAATTCGACCTCGATTGCGCGCTCGTGTGCGCGCGCCTGCATGGCCACGGCCATGCGCACGGCGTCGATGG
ACAGATCGCGGCGATGGGTATCGCCTATGGTTTGACGGTGGTCAGCGGCAGGCTTGACAGTTTCGTGACGCAGGGACTGC
GGCTGGAAAATCCGTTTAGTTGA

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 8000.17 Da        Isoelectric Point: 6.4770

>AT127764 WP_141171808.1 NZ_CP041185:5171578-5171787 [Janthinobacterium tructae]
MPLTLIFTDTDELLIAALHKRARAHGRSLEEEHRDILRSALRPLPKRPLDDILRSMPDVEHDADFQRCS

Download         Length: 210 bp

>AT127764 NZ_CP041185:5171578-5171787 [Janthinobacterium tructae]
ATGCCGCTGACACTGATCTTTACCGATACCGATGAATTACTGATCGCCGCGCTGCACAAGCGTGCCCGCGCGCATGGGCG
CAGCCTCGAAGAGGAGCACCGCGACATCCTGCGCAGCGCCTTGCGACCGCTGCCGAAGCGTCCGCTCGACGATATTCTGC
GCAGCATGCCCGACGTGGAGCACGACGCGGATTTCCAGCGCTGCTCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References