Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3080899..3081415 Replicon chromosome
Accession NZ_CP041151
Organism Shewanella sp. SNU WT4 strain SNU WT1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FJQ87_RS13825 Protein ID WP_140933113.1
Coordinates 3080899..3081183 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FJQ87_RS13830 Protein ID WP_140934134.1
Coordinates 3081173..3081415 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJQ87_RS13800 3076462..3076983 - 522 WP_140934133.1 MarR family winged helix-turn-helix transcriptional regulator -
FJQ87_RS13805 3077141..3077305 + 165 Protein_2607 haloalkane dehalogenase -
FJQ87_RS18780 3078950..3079165 + 216 WP_206194347.1 hypothetical protein -
FJQ87_RS13820 3079202..3080629 + 1428 WP_140933112.1 IS4 family transposase -
FJQ87_RS13825 3080899..3081183 - 285 WP_140933113.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FJQ87_RS13830 3081173..3081415 - 243 WP_140934134.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FJQ87_RS13835 3081529..3082080 + 552 Protein_2613 transposase family protein -
FJQ87_RS13840 3082102..3082527 + 426 Protein_2614 IS3 family transposase -
FJQ87_RS13845 3082660..3085908 - 3249 WP_140933114.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 3077344..3082527 5183


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11195.23 Da        Isoelectric Point: 10.4231

>T127742 WP_140933113.1 NZ_CP041151:c3081183-3080899 [Shewanella sp. SNU WT4]
MIYKLEFDPRALKEWKKLGDPIRQQLKKKLAEILQHPHIEANKLRDLPDCYKIKLRTSGYRLVYQVQDERITVFVVAVGK
RERLAVYSTAEKRL

Download         Length: 285 bp

>T127742 NZ_CP041151:c3081183-3080899 [Shewanella sp. SNU WT4]
ATGATCTATAAGTTAGAGTTTGATCCCCGCGCACTAAAGGAATGGAAGAAGCTCGGAGATCCCATTAGACAGCAATTAAA
AAAGAAACTGGCCGAGATCCTACAACATCCTCATATCGAGGCCAACAAACTTAGAGATCTCCCTGACTGTTACAAAATCA
AATTGCGCACATCAGGTTATCGCTTGGTATATCAAGTGCAAGATGAACGCATTACCGTGTTTGTAGTCGCTGTAGGCAAG
CGTGAACGATTAGCAGTGTATTCAACAGCAGAAAAGCGTCTTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8930.33 Da        Isoelectric Point: 4.3449

>AT127742 WP_140934134.1 NZ_CP041151:c3081415-3081173 [Shewanella sp. SNU WT4]
MGTISIRIDDELKERSYAALDKLGITPSEALRQMLEYVATRETLPFKSVLLTAEDEALIALVKERLANPLRGIEVSLDDL

Download         Length: 243 bp

>AT127742 NZ_CP041151:c3081415-3081173 [Shewanella sp. SNU WT4]
ATGGGAACAATTAGTATTCGTATAGATGATGAGCTTAAAGAGCGTTCTTATGCTGCGTTGGATAAACTAGGCATCACACC
TTCTGAGGCGTTGCGTCAAATGCTTGAATATGTCGCCACAAGGGAAACTTTGCCATTCAAGTCTGTGCTGCTAACCGCAG
AAGATGAAGCCTTGATTGCTTTAGTTAAAGAACGTTTAGCAAACCCTCTAAGGGGGATTGAAGTGTCGCTCGATGATCTA
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References