Detailed information of TA system TA127741

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 3075146..3076164
• Replicon: chromosome
• Accession: NZ_CP041151
• Organism: Shewanella sp. SNU WT4 strain SNU WT1

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: FJQ87_RS13795
• Protein ID: WP_140933111.1
• Coordinates: 3075595..3076164 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: FJQ87_RS13790
• Protein ID: WP_140934132.1
• Coordinates: 3075146..3075595 (+)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FJQ87_RS13775	3070189..3073590	+	3402	WP_140933110.1	glycosyl transferase	-
FJQ87_RS13780	3073704..3074144	-	441	Protein_2602	IS66 family transposase	-
FJQ87_RS13785	3074478..3074858	+	381	WP_140934131.1	hypothetical protein	-
FJQ87_RS13790	3075146..3075595	+	450	WP_140934132.1	excisionase family DNA-binding protein	Antitoxin
FJQ87_RS13795	3075595..3076164	+	570	WP_140933111.1	PIN domain-containing protein	Toxin
FJQ87_RS13800	3076462..3076983	-	522	WP_140934133.1	MarR family winged helix-turn-helix transcriptional regulator	-
FJQ87_RS13805	3077141..3077305	+	165	Protein_2607	haloalkane dehalogenase	-
FJQ87_RS18780	3078950..3079165	+	216	WP_206194347.1	hypothetical protein	-
FJQ87_RS13820	3079202..3080629	+	1428	WP_140933112.1	IS4 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-113)

Antitoxin

• SinI-like, DNA-binding domain (79-126)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21634.19 Da
• Isoelectric Point: 5.0500

>T127741 WP_140933111.1 NZ_CP041151:3075595-3076164 [Shewanella sp. SNU WT4]
MASYTVVFDACVMYPAPLRSYLMYLANAGLFRARWTEQIHDEWMRNVLLNNPRITEAMLERTKQLINENVPDCLIEGYEP
LIKGLTLPDMNDRHVVAAALKGHAEAIITFNLKDFPESELNILELSAIHPDEFLCDMFELDPSSCIKAAQQQRSSLKNPA
MTVSEFLNCLQKQKLPVFVSKLRPFELML

Nucleotide

• Length: 570 bp

>T127741 NZ_CP041151:3075595-3076164 [Shewanella sp. SNU WT4]
ATGGCTTCGTATACTGTTGTTTTTGATGCGTGTGTCATGTATCCCGCGCCACTTCGTAGTTATTTGATGTATTTAGCAAA
TGCGGGCTTATTTAGGGCTCGCTGGACTGAGCAAATCCATGATGAATGGATGCGTAATGTATTGCTGAATAATCCACGCA
TCACAGAAGCAATGTTAGAACGAACGAAACAACTGATTAATGAAAATGTACCTGATTGCCTTATTGAAGGGTATGAGCCG
TTAATTAAAGGATTAACACTGCCTGATATGAATGATAGGCATGTGGTTGCTGCGGCTTTAAAAGGGCACGCAGAGGCCAT
CATAACGTTTAATCTTAAGGATTTTCCTGAGTCAGAACTCAATATACTTGAACTATCAGCTATCCATCCTGATGAGTTTT
TGTGCGACATGTTTGAGTTAGATCCAAGCTCTTGTATCAAAGCTGCTCAACAGCAAAGAAGTAGCTTAAAGAATCCCGCG
ATGACAGTATCAGAGTTTTTAAATTGCTTACAAAAGCAAAAATTACCGGTTTTTGTTTCGAAGCTGAGACCATTTGAATT
AATGCTATGA

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 16639.12 Da
• Isoelectric Point: 5.7424

>AT127741 WP_140934132.1 NZ_CP041151:3075146-3075595 [Shewanella sp. SNU WT4]
MNMTTLPNAEQIAMARLGSQELSAVIESNGEAQQISVIDKQGQSHDVILPSSVLKMMIEMLTQLGQGNSVNITPIHAEMT
TQQGADFLNMSRPTFIKLLDSREISFTRVGNRRKVPFSAVIKYKQQLEIQRLSTLDELSRLDQELGMGY

Nucleotide

• Length: 450 bp

>AT127741 NZ_CP041151:3075146-3075595 [Shewanella sp. SNU WT4]
ATGAACATGACTACTTTACCGAACGCAGAACAAATCGCAATGGCTCGGTTGGGCAGCCAGGAGTTATCTGCTGTTATTGA
AAGTAACGGTGAGGCTCAACAAATAAGTGTAATTGATAAACAAGGTCAATCACATGATGTCATTTTACCTTCTAGCGTAT
TGAAAATGATGATTGAAATGTTGACGCAATTGGGACAGGGTAATTCTGTTAACATCACTCCCATACATGCCGAAATGACC
ACACAACAAGGCGCTGATTTTTTGAATATGTCACGACCAACATTTATCAAGTTATTAGATTCACGTGAAATATCATTTAC
TCGAGTCGGTAATCGAAGAAAAGTGCCATTTTCTGCGGTGATAAAATATAAGCAGCAACTGGAAATTCAACGTTTGTCAA
CACTTGATGAGCTTTCCAGATTAGATCAGGAATTGGGTATGGGTTACTAA