Detailed information of TA system TA127740

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /DUF1778(antitoxin)
• Location: 3066645..3067444
• Replicon: chromosome
• Accession: NZ_CP041151
• Organism: Shewanella sp. SNU WT4 strain SNU WT1

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FJQ87_RS13750
• Protein ID: WP_140933107.1
• Coordinates: 3066645..3067178 (-)
• Length: 178 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FJQ87_RS13755
• Protein ID: WP_140933108.1
• Coordinates: 3067175..3067444 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FJQ87_RS13710	3062322..3063164	-	843	Protein_2588	DUF86 domain-containing protein	-
FJQ87_RS13715	3063230..3063514	-	285	WP_140933103.1	type II toxin-antitoxin system RelE/ParE family toxin	-
FJQ87_RS13720	3063504..3063752	-	249	WP_140934129.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
FJQ87_RS13725	3063908..3065344	-	1437	WP_140933104.1	IS66 family transposase	-
FJQ87_RS13730	3065447..3065794	-	348	WP_140933105.1	IS66 family insertion sequence element accessory protein TnpB	-
FJQ87_RS13735	3065791..3066063	-	273	WP_140933106.1	IS66 family insertion sequence element accessory protein TnpB	-
FJQ87_RS13740	3066157..3066444	+	288	Protein_2594	IS21-like element ISSba11 family helper ATPase IstB	-
FJQ87_RS13745	3066515..3066625	-	111	Protein_2595	DUF3265 domain-containing protein	-
FJQ87_RS13750	3066645..3067178	-	534	WP_140933107.1	GNAT family N-acetyltransferase	Toxin
FJQ87_RS13755	3067175..3067444	-	270	WP_140933108.1	DUF1778 domain-containing protein	Antitoxin
FJQ87_RS13760	3067568..3067789	+	222	Protein_2598	IS1634 family transposase	-
FJQ87_RS13765	3067925..3069115	-	1191	WP_140933109.1	J domain-containing protein	-
FJQ87_RS13770	3069464..3069723	-	260	Protein_2600	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	3066187..3066444	257

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (97-153)

Antitoxin

• Vibrio phage ICP1, Orf50 (5-81)

Sequences

Toxin

Protein

• Length: 178 a.a.
• Molecular weight: 20193.60 Da
• Isoelectric Point: 9.9958

>T127740 WP_140933107.1 NZ_CP041151:c3067178-3066645 [Shewanella sp. SNU WT4]
VSWGKEFVEFSKSKHDRDSFDCGEQGLNTFIKIQAAKHMQAGISRTMVLPSAQPLLNKKFAICAFYSVAPSSISRETLPT
QRVKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRVYAIVVDCLTDSAQAFYTKFGFEVLCEHNG
RIRMFLPMKTVEQLFNQ

Nucleotide

• Length: 534 bp

>T127740 NZ_CP041151:c3067178-3066645 [Shewanella sp. SNU WT4]
GTGAGTTGGGGCAAAGAGTTTGTAGAATTTAGTAAATCAAAGCATGACCGCGACTCATTTGACTGTGGTGAGCAAGGGCT
AAACACATTTATTAAAATTCAAGCTGCAAAGCACATGCAAGCAGGTATTAGCCGAACAATGGTTTTACCTAGTGCTCAAC
CACTGCTAAATAAAAAATTCGCTATTTGTGCATTTTATAGTGTTGCACCAAGTTCAATCAGTCGAGAAACTTTGCCGACA
CAACGAGTAAAAAAACTTCCTAGGTATCCAATACCTGTTTTTCTTTTGGCTCAATTAGCTGTGCACAAAGAGTTTCATGG
CTCTGGGCTCGGAAAAGTTAGTCTAATTCGCGCGCTGAAGTACTTGTGGGAAGTGAATCATCACATGAGGGTATACGCAA
TTGTTGTGGACTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTCGGCTTTGAAGTGTTATGCGAACATAATGGG
CGTATTCGTATGTTCTTACCAATGAAAACGGTAGAACAGCTTTTTAATCAATAG

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9965.59 Da
• Isoelectric Point: 5.1889

>AT127740 WP_140933108.1 NZ_CP041151:c3067444-3067175 [Shewanella sp. SNU WT4]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDENATHVIEEHESLMVKDSLFDEFMVACNKVKAPNQALLEAV
KFTEKSGIK

Nucleotide

• Length: 270 bp

>AT127740 NZ_CP041151:c3067444-3067175 [Shewanella sp. SNU WT4]
ATGGCAACGGCACGTTTAGATATCCGCCTTGATGAAGAAATCAAGGCAAAAGCCGAAAAAGCATCGGCTTTACTTGGTTT
AAAAAGTCTCACTGAATATGTGGTGAGACTTATGGATGAAAATGCGACTCATGTTATTGAGGAGCATGAAAGTCTTATGG
TTAAAGACAGTCTTTTTGACGAGTTTATGGTTGCGTGTAATAAAGTAAAAGCACCGAATCAAGCTTTGCTTGAAGCTGTT
AAATTTACAGAAAAGAGCGGTATCAAGTGA