Detailed information of TA system TA127739

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3063230..3063752
• Replicon: chromosome
• Accession: NZ_CP041151
• Organism: Shewanella sp. SNU WT4 strain SNU WT1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FJQ87_RS13715
• Protein ID: WP_140933103.1
• Coordinates: 3063230..3063514 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FJQ87_RS13720
• Protein ID: WP_140934129.1
• Coordinates: 3063504..3063752 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FJQ87_RS13690	3058470..3059018	-	549	WP_140933100.1	dTDP-4-dehydrorhamnose 3,5-epimerase	-
FJQ87_RS13695	3059080..3059958	-	879	WP_140934128.1	dTDP-4-dehydrorhamnose reductase	-
FJQ87_RS13700	3059972..3060844	-	873	WP_140933101.1	glucose-1-phosphate thymidylyltransferase RfbA	-
FJQ87_RS13705	3060986..3062065	-	1080	WP_140933102.1	dTDP-glucose 4,6-dehydratase	-
FJQ87_RS13710	3062322..3063164	-	843	Protein_2588	DUF86 domain-containing protein	-
FJQ87_RS13715	3063230..3063514	-	285	WP_140933103.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FJQ87_RS13720	3063504..3063752	-	249	WP_140934129.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FJQ87_RS13725	3063908..3065344	-	1437	WP_140933104.1	IS66 family transposase	-
FJQ87_RS13730	3065447..3065794	-	348	WP_140933105.1	IS66 family insertion sequence element accessory protein TnpB	-
FJQ87_RS13735	3065791..3066063	-	273	WP_140933106.1	IS66 family insertion sequence element accessory protein TnpB	-
FJQ87_RS13740	3066157..3066444	+	288	Protein_2594	IS21-like element ISSba11 family helper ATPase IstB	-
FJQ87_RS13745	3066515..3066625	-	111	Protein_2595	DUF3265 domain-containing protein	-
FJQ87_RS13750	3066645..3067178	-	534	WP_140933107.1	GNAT family N-acetyltransferase	-
FJQ87_RS13755	3067175..3067444	-	270	WP_140933108.1	DUF1778 domain-containing protein	-
FJQ87_RS13760	3067568..3067789	+	222	Protein_2598	IS1634 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	3066187..3066444	257

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11125.19 Da
• Isoelectric Point: 10.7043

>T127739 WP_140933103.1 NZ_CP041151:c3063514-3063230 [Shewanella sp. SNU WT4]
MTYKLVFKVEAEKEWKKLDPTIKVKFKKRVLERLDNPHVPSSKLSGMQNCYKIKLRSAGYRLVYEVRDEQIIVSVVSVGK
RERNEVFKNAIKRI

Nucleotide

• Length: 285 bp

>T127739 NZ_CP041151:c3063514-3063230 [Shewanella sp. SNU WT4]
ATGACTTATAAGCTGGTATTTAAGGTTGAAGCCGAGAAAGAGTGGAAAAAGCTAGACCCAACAATCAAAGTAAAGTTTAA
AAAAAGAGTATTAGAGAGGCTTGATAATCCACATGTGCCATCATCCAAGCTAAGTGGAATGCAAAATTGCTACAAAATCA
AGCTGCGTAGTGCTGGTTATCGCTTAGTTTATGAAGTTAGAGATGAGCAAATTATTGTATCAGTTGTATCTGTGGGTAAG
CGGGAGCGTAATGAAGTATTTAAGAATGCAATAAAGCGTATTTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9155.44 Da
• Isoelectric Point: 4.1064

>AT127739 WP_140934129.1 NZ_CP041151:c3063752-3063504 [Shewanella sp. SNU WT4]
MIRPILADNATSISELKKNPMAVVEGADGFPVAVLNRNQPAFYCVPAEAYELLMDKLEDIELAQLVRERQHSDEVEVSLN
DL

Nucleotide

• Length: 249 bp

>AT127739 NZ_CP041151:c3063752-3063504 [Shewanella sp. SNU WT4]
ATGATACGTCCAATTCTTGCAGATAATGCAACGAGCATCAGCGAGCTAAAGAAAAATCCAATGGCGGTAGTCGAGGGTGC
CGATGGTTTTCCTGTTGCTGTTTTGAATAGAAATCAGCCAGCTTTTTATTGCGTCCCTGCCGAGGCATATGAGCTGTTAA
TGGACAAGCTGGAAGATATTGAATTAGCTCAGTTGGTTCGCGAGCGTCAGCATTCAGATGAGGTCGAGGTTTCTTTGAAT
GACTTATAA