Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 2991956..2992722 Replicon chromosome
Accession NZ_CP041151
Organism Shewanella sp. SNU WT4 strain SNU WT1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FJQ87_RS13305 Protein ID WP_140933050.1
Coordinates 2991956..2992453 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FJQ87_RS13310 Protein ID WP_140933051.1
Coordinates 2992450..2992722 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJQ87_RS13290 2987779..2989227 + 1449 WP_140933047.1 sodium/proline symporter PutP -
FJQ87_RS13295 2989697..2990950 + 1254 WP_140933048.1 outer membrane protein transport protein -
FJQ87_RS13300 2991120..2991830 + 711 WP_140933049.1 SIMPL domain-containing protein -
FJQ87_RS13305 2991956..2992453 - 498 WP_140933050.1 GNAT family N-acetyltransferase Toxin
FJQ87_RS13310 2992450..2992722 - 273 WP_140933051.1 DUF1778 domain-containing protein Antitoxin
FJQ87_RS13315 2992828..2993192 - 365 Protein_2525 helix-turn-helix domain-containing protein -
FJQ87_RS13320 2993268..2993717 + 450 WP_140933052.1 IS200/IS605 family transposase -
FJQ87_RS13325 2993918..2995024 + 1107 WP_168195198.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(86-149)

Antitoxin

Vibrio phage ICP1, Orf50

(7-86)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18660.29 Da        Isoelectric Point: 8.0627

>T127738 WP_140933050.1 NZ_CP041151:c2992453-2991956 [Shewanella sp. SNU WT4]
MMNTVLLDKDKHDRNRFNCGVEALNNYLKVMASQQAKKDNTRTFVLEDDHDNSHIIGFYTLTMTPIDLKALPDKLQKKHQ
SSTSGGLIARLAVDDRYKGKGFGEWVLIDALRKLLAASDSVAFPVVIVDAKDGAKYFYERYGFQAFQHSENKLFITIDDI
RASLG

Download         Length: 498 bp

>T127738 NZ_CP041151:c2992453-2991956 [Shewanella sp. SNU WT4]
ATGATGAATACGGTGCTTCTAGATAAAGATAAGCACGATAGAAACCGATTCAACTGTGGAGTCGAAGCTCTCAATAATTA
TTTAAAAGTAATGGCTAGTCAGCAAGCAAAGAAAGACAACACCAGAACTTTCGTTTTGGAAGATGATCACGACAACTCAC
ATATTATTGGTTTTTACACGCTAACAATGACACCAATTGACTTAAAGGCATTGCCCGATAAGTTACAGAAGAAGCACCAA
TCGTCTACTTCAGGTGGTCTCATTGCTCGTTTAGCTGTCGATGACCGATATAAAGGGAAAGGCTTTGGCGAGTGGGTGCT
TATCGACGCACTCCGAAAGCTATTAGCGGCTAGTGACAGCGTCGCCTTTCCTGTAGTTATCGTTGACGCCAAAGATGGCG
CAAAATACTTCTATGAACGTTATGGATTTCAAGCGTTTCAACATTCAGAGAACAAACTCTTCATCACCATCGATGATATC
AGAGCAAGTTTAGGCTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9770.36 Da        Isoelectric Point: 8.5960

>AT127738 WP_140933051.1 NZ_CP041151:c2992722-2992450 [Shewanella sp. SNU WT4]
MATTLPRITARVDVDTQDLLTKAAAIAGMSSINSFVLSAAIEKAKQVIDREQALKLSQADAMLLMEALDRPATPNPKLKI
ASDRYESKIQ

Download         Length: 273 bp

>AT127738 NZ_CP041151:c2992722-2992450 [Shewanella sp. SNU WT4]
ATGGCTACTACTTTGCCTCGCATCACCGCTAGAGTTGATGTCGACACACAAGATTTACTTACAAAAGCTGCTGCTATTGC
TGGCATGTCCAGTATTAATTCATTTGTTTTAAGTGCTGCAATTGAAAAAGCCAAACAAGTAATCGATCGTGAGCAAGCTC
TAAAACTGAGCCAAGCTGACGCTATGTTGTTAATGGAAGCCTTAGACCGCCCTGCAACACCTAATCCTAAATTGAAAATA
GCTTCTGACCGCTACGAGAGTAAAATTCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References