Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2091442..2091586 Replicon chromosome
Accession NZ_CP041134
Organism Serratia marcescens strain WVU-010

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2091486..2091582 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2091442..2091586 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FG175_RS10025 2086640..2087065 + 426 WP_033653830.1 RNA polymerase-binding protein DksA -
FG175_RS10030 2087260..2088213 + 954 WP_141958825.1 prolyl aminopeptidase -
FG175_RS10035 2088247..2088477 - 231 WP_033638067.1 DNA polymerase III subunit theta -
FG175_RS10040 2088822..2089340 + 519 WP_141958827.1 non-heme ferritin -
FG175_RS10045 2089633..2090049 + 417 WP_046686875.1 CopC domain-containing protein YobA -
FG175_RS10050 2090052..2090933 + 882 WP_126193118.1 copper homeostasis membrane protein CopD -
FG175_RS10055 2091003..2091344 + 342 WP_025302452.1 YebY family protein -
- 2091442..2091586 - 145 - - Antitoxin
- 2091486..2091582 + 97 - - Toxin
FG175_RS10060 2091661..2092743 - 1083 WP_141958829.1 phage integrase Arm DNA-binding domain-containing protein -
FG175_RS10065 2092718..2092990 - 273 WP_072022390.1 hypothetical protein -
FG175_RS10070 2093066..2093569 - 504 WP_060444327.1 siphovirus Gp157 family protein -
FG175_RS10075 2093566..2095698 - 2133 WP_141958831.1 hypothetical protein -
FG175_RS10080 2095713..2096033 - 321 WP_141958833.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2084830..2173825 88995


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T127706 NZ_CP041134:2091486-2091582 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 145 bp

>AT127706 NZ_CP041134:c2091586-2091442 [Serratia marcescens]
AGTTAAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References