Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4962202..4962794 Replicon chromosome
Accession NZ_CP041130
Organism Serratia marcescens strain WVU-007

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag FG172_RS23930 Protein ID WP_141960450.1
Coordinates 4962444..4962794 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag FG172_RS23925 Protein ID WP_049300713.1
Coordinates 4962202..4962450 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FG172_RS23905 4958019..4958357 + 339 WP_038878111.1 PTS lactose/cellobiose transporter subunit IIA -
FG172_RS23910 4958354..4959661 + 1308 WP_141960449.1 6-phospho-beta-glucosidase -
FG172_RS23915 4959735..4960715 + 981 WP_070914492.1 LacI family transcriptional regulator -
FG172_RS23920 4960907..4962091 + 1185 WP_033636290.1 MFS transporter TsgA -
FG172_RS23925 4962202..4962450 + 249 WP_049300713.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FG172_RS23930 4962444..4962794 + 351 WP_141960450.1 type II toxin-antitoxin system ChpB family toxin Toxin
FG172_RS23935 4962791..4964074 - 1284 WP_141960452.1 cytosine deaminase -
FG172_RS23945 4964363..4966912 + 2550 WP_141960454.1 nitrite reductase large subunit NirB -
FG172_RS23950 4966909..4967235 + 327 WP_038878129.1 nitrite reductase small subunit NirD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-82)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12390.38 Da        Isoelectric Point: 11.5657

>T127699 WP_141960450.1 NZ_CP041130:4962444-4962794 [Serratia marcescens]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTGGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFIERAPGEVIADALARLQAIID

Download         Length: 351 bp

>T127699 NZ_CP041130:4962444-4962794 [Serratia marcescens]
ATGGTGAAGCGCCCCGTTTTTCAGCGCGGAGATCTTATCCGGGTCAGCCTGAATCCCGTGGTTGGCCGTGAGCAGCAAGG
CGACTTTCGTCCGGCACTGGTGCTCTCTCCCCGCGAGTTTAATGCGCTGGGCATGGTGCTGGTCGCCCCTATTTCGCAAG
GGGCTAATTTTGCCCGTACAGGGGGTTTCACCGTCAGCCTGAGCGGGAGCGGCACCGCAACGCAGGGCGTCATCTTGATC
AACCAGGTTCGCATGATGGATCTGGCCGGGCGCAGCGCGCAATTCATTGAACGTGCCCCTGGCGAAGTCATCGCCGACGC
GCTGGCGCGGCTTCAGGCAATCATCGACTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9069.53 Da        Isoelectric Point: 4.5026

>AT127699 WP_049300713.1 NZ_CP041130:4962202-4962450 [Serratia marcescens]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALVIKPVKKRYSLQQLLDGCDGEAPAAADDNWEHMPPAGKE
VW

Download         Length: 249 bp

>AT127699 NZ_CP041130:4962202-4962450 [Serratia marcescens]
ATGAAAGTCTTTATCAAAAAATGGGGCAACAGCGCGGGAATGCTGGTGCCCTCAGCGCTAATGAACGAGCTGGAACTCCA
GGTAGGTCAGGAAATGGACATGCAGGTCATCGATGGAGCGTTGGTCATTAAGCCGGTTAAGAAACGCTATTCACTGCAGC
AATTGCTCGATGGCTGCGACGGTGAAGCGCCGGCCGCCGCAGACGACAACTGGGAACACATGCCGCCGGCGGGGAAAGAA
GTATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References