Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2091472..2091616 Replicon chromosome
Accession NZ_CP041130
Organism Serratia marcescens strain WVU-007

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2091516..2091612 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2091472..2091616 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FG172_RS10025 2086670..2087095 + 426 WP_033653830.1 RNA polymerase-binding protein DksA -
FG172_RS10030 2087290..2088243 + 954 WP_141958825.1 prolyl aminopeptidase -
FG172_RS10035 2088277..2088507 - 231 WP_033638067.1 DNA polymerase III subunit theta -
FG172_RS10040 2088852..2089370 + 519 WP_141958827.1 non-heme ferritin -
FG172_RS10045 2089663..2090079 + 417 WP_046686875.1 CopC domain-containing protein YobA -
FG172_RS10050 2090082..2090963 + 882 WP_126193118.1 copper homeostasis membrane protein CopD -
FG172_RS10055 2091033..2091374 + 342 WP_025302452.1 YebY family protein -
- 2091472..2091616 - 145 - - Antitoxin
- 2091516..2091612 + 97 - - Toxin
FG172_RS10060 2091691..2092773 - 1083 WP_141958829.1 phage integrase Arm DNA-binding domain-containing protein -
FG172_RS10065 2092748..2093020 - 273 WP_072022390.1 hypothetical protein -
FG172_RS10070 2093096..2093599 - 504 WP_060444327.1 siphovirus Gp157 family protein -
FG172_RS10075 2093596..2095728 - 2133 WP_141958831.1 hypothetical protein -
FG172_RS10080 2095743..2096063 - 321 WP_141958833.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2084860..2173855 88995


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T127683 NZ_CP041130:2091516-2091612 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 145 bp

>AT127683 NZ_CP041130:c2091616-2091472 [Serratia marcescens]
AGTTAAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References