Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2091829..2091973 Replicon chromosome
Accession NZ_CP041125
Organism Serratia marcescens strain WVU-004

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2091873..2091969 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2091829..2091973 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FG169_RS10040 2087027..2087452 + 426 WP_033653830.1 RNA polymerase-binding protein DksA -
FG169_RS10045 2087647..2088600 + 954 WP_141958825.1 prolyl aminopeptidase -
FG169_RS10050 2088634..2088864 - 231 WP_033638067.1 DNA polymerase III subunit theta -
FG169_RS10055 2089209..2089727 + 519 WP_141958827.1 non-heme ferritin -
FG169_RS10060 2090020..2090436 + 417 WP_046686875.1 CopC domain-containing protein YobA -
FG169_RS10065 2090439..2091320 + 882 WP_126193118.1 copper homeostasis membrane protein CopD -
FG169_RS10070 2091390..2091731 + 342 WP_025302452.1 YebY family protein -
- 2091829..2091973 - 145 - - Antitoxin
- 2091873..2091969 + 97 - - Toxin
FG169_RS10075 2092048..2093130 - 1083 WP_141958829.1 phage integrase Arm DNA-binding domain-containing protein -
FG169_RS10080 2093105..2093377 - 273 WP_072022390.1 hypothetical protein -
FG169_RS10085 2093453..2093956 - 504 WP_060444327.1 siphovirus Gp157 family protein -
FG169_RS10090 2093953..2096085 - 2133 WP_141958831.1 hypothetical protein -
FG169_RS10095 2096100..2096420 - 321 WP_141958833.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2085217..2135592 50375


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T127660 NZ_CP041125:2091873-2091969 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 145 bp

>AT127660 NZ_CP041125:c2091973-2091829 [Serratia marcescens]
AGTTAAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References