Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1994315..1994586 Replicon chromosome
Accession NZ_CP041110
Organism Escherichia coli strain ECCTRSRTH03

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1994445..1994548 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1994315..1994586 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CI675_RS09675 1990870..1991532 - 663 WP_000944256.1 exodeoxyribonuclease X -
CI675_RS09680 1991556..1992212 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CI675_RS09685 1992314..1992544 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CI675_RS09690 1992683..1993057 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CI675_RS09695 1993061..1993933 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
CI675_RS09700 1993946..1994287 + 342 WP_000976476.1 YebY family protein -
- 1994315..1994586 - 272 - - Antitoxin
- 1994445..1994548 + 104 - - Toxin
CI675_RS09705 1994683..1995339 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
CI675_RS09710 1995340..1995531 - 192 WP_000457842.1 YebW family protein -
CI675_RS09715 1995636..1995872 - 237 WP_001295499.1 DUF1480 family protein -
CI675_RS09720 1995990..1997429 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1931239..2010426 79187


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T127606 NZ_CP041110:1994445-1994548 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT127606 NZ_CP041110:c1994586-1994315 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References