Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1865069..1865214 Replicon chromosome
Accession NZ_CP041092
Organism Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1865105..1865207 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1865069..1865214 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CI667_RS09090 1860199..1862259 + 2061 WP_004151449.1 oligopeptidase B -
CI667_RS09095 1862263..1862922 - 660 WP_040224088.1 exodeoxyribonuclease X -
CI667_RS09100 1863001..1863231 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CI667_RS09105 1863344..1863718 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CI667_RS09110 1863722..1864591 + 870 WP_094487628.1 copper homeostasis membrane protein CopD -
CI667_RS09115 1864608..1864946 + 339 WP_002911404.1 YebY family protein -
- 1865069..1865214 - 146 - - Antitoxin
- 1865105..1865207 + 103 - - Toxin
CI667_RS09125 1865583..1865726 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CI667_RS09130 1865831..1866799 - 969 WP_004151446.1 VirK/YbjX family protein -
CI667_RS09135 1866956..1867609 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CI667_RS09140 1867606..1867797 - 192 WP_002911395.1 YebW family protein -
CI667_RS09145 1867895..1868134 - 240 WP_002911393.1 YebV family protein -
CI667_RS09150 1868250..1869683 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T127575 NZ_CP041092:1865105-1865207 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT127575 NZ_CP041092:c1865214-1865069 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References