Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 2777502..2778087 Replicon chromosome
Accession NZ_CP041090
Organism Bradyrhizobium symbiodeficiens strain 65S1MB

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FJN17_RS12775 Protein ID WP_140479983.1
Coordinates 2777791..2778087 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FJN17_RS12770 Protein ID WP_140479982.1
Coordinates 2777502..2777789 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJN17_RS12745 2773213..2773434 + 222 WP_140479979.1 hypothetical protein -
FJN17_RS12750 2773490..2774122 - 633 WP_094891777.1 ATP-dependent Clp protease proteolytic subunit -
FJN17_RS12755 2774402..2775763 - 1362 WP_140479980.1 trigger factor -
FJN17_RS12765 2776176..2777492 + 1317 WP_140479981.1 multicopper oxidase domain-containing protein -
FJN17_RS12770 2777502..2777789 - 288 WP_140479982.1 putative addiction module antidote protein Antitoxin
FJN17_RS12775 2777791..2778087 - 297 WP_140479983.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FJN17_RS12780 2778097..2778489 - 393 WP_162859520.1 GNAT family N-acetyltransferase -
FJN17_RS12785 2778561..2780060 - 1500 WP_140479985.1 NAD(P)H-hydrate dehydratase -
FJN17_RS12790 2780442..2780780 + 339 WP_007603495.1 P-II family nitrogen regulator -
FJN17_RS12795 2780932..2782341 + 1410 WP_094891781.1 type I glutamate--ammonia ligase -
FJN17_RS12800 2782418..2782681 - 264 WP_094891782.1 4-oxalocrotonate tautomerase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(4-92)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11109.83 Da        Isoelectric Point: 10.9403

>T127567 WP_140479983.1 NZ_CP041090:c2778087-2777791 [Bradyrhizobium symbiodeficiens]
VVELKQTETFRKWRSRLRDQRARALIASRLDRLAQGHLGDVEPVGDGISELRIHYGPGYRVYFQKRGNTIIILLCGGDKS
TQAKDIKAARSLAAMWSK

Download         Length: 297 bp

>T127567 NZ_CP041090:c2778087-2777791 [Bradyrhizobium symbiodeficiens]
GTGGTCGAGCTCAAGCAAACCGAGACGTTTCGAAAGTGGCGATCGCGTCTCCGGGATCAGCGAGCCAGGGCGTTGATTGC
CTCGCGCCTGGATCGGTTGGCTCAGGGACACCTTGGCGACGTCGAGCCCGTGGGCGATGGAATAAGCGAATTGCGTATCC
ATTACGGGCCAGGCTACCGCGTCTATTTTCAGAAGCGGGGCAATACGATCATCATTTTGCTGTGCGGTGGCGACAAGAGC
ACGCAGGCGAAAGACATCAAGGCGGCAAGGAGCCTTGCCGCCATGTGGAGCAAATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10275.71 Da        Isoelectric Point: 5.0893

>AT127567 WP_140479982.1 NZ_CP041090:c2777789-2777502 [Bradyrhizobium symbiodeficiens]
MAEKLTTYDPAEDLQSDEAIAVFMEEAFKTEDAAYIAHALGVVARAKGMTQIAKDTGLSREQLYRSFSTNGNPTLKTTIA
VMKALGIELTAKPHA

Download         Length: 288 bp

>AT127567 NZ_CP041090:c2777789-2777502 [Bradyrhizobium symbiodeficiens]
ATGGCCGAGAAGCTGACGACTTATGATCCGGCCGAGGACCTTCAGTCTGACGAGGCGATTGCCGTCTTCATGGAGGAGGC
GTTCAAGACGGAGGATGCGGCCTATATCGCACATGCGCTTGGCGTCGTCGCCCGTGCCAAAGGTATGACGCAGATCGCCA
AGGATACCGGCCTGTCTCGCGAGCAACTCTATCGCTCGTTCAGCACCAACGGTAATCCGACTCTCAAGACGACGATCGCG
GTGATGAAGGCGCTTGGAATCGAGCTCACGGCCAAGCCGCACGCCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References