Detailed information of TA system TA127566

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 2243527..2244125
• Replicon: chromosome
• Accession: NZ_CP041090
• Organism: Bradyrhizobium symbiodeficiens strain 65S1MB

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FJN17_RS10275
• Protein ID: WP_140479518.1
• Coordinates: 2243527..2243820 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FJN17_RS10280
• Protein ID: WP_140479520.1
• Coordinates: 2243817..2244125 (-)
• Length: 103 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FJN17_RS10235	2238544..2240208	+	1665	WP_140479508.1	hypothetical protein	-
FJN17_RS10245	2240523..2240777	+	255	WP_094974274.1	PilZ domain-containing protein	-
FJN17_RS10250	2240834..2241079	+	246	WP_094974273.1	hypothetical protein	-
FJN17_RS34465	2241085..2241252	+	168	WP_140479510.1	hypothetical protein	-
FJN17_RS10260	2241380..2242018	-	639	WP_140479512.1	glutathione S-transferase	-
FJN17_RS10265	2242322..2242774	-	453	WP_140479514.1	VOC family protein	-
FJN17_RS10270	2243037..2243204	+	168	WP_140479516.1	H-NS histone family protein	-
FJN17_RS10275	2243527..2243820	-	294	WP_140479518.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FJN17_RS10280	2243817..2244125	-	309	WP_140479520.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
FJN17_RS10285	2244196..2244474	+	279	WP_140479522.1	hypothetical protein	-
FJN17_RS34025	2244606..2244743	+	138	WP_155527927.1	hypothetical protein	-
FJN17_RS10290	2244920..2245192	-	273	WP_094974269.1	hypothetical protein	-
FJN17_RS10295	2245414..2245716	-	303	WP_094974268.1	hypothetical protein	-
FJN17_RS10300	2245829..2246320	-	492	WP_140479524.1	hypothetical protein	-
FJN17_RS10305	2246671..2246967	+	297	WP_094896974.1	HU family DNA-binding protein	-
FJN17_RS34470	2247425..2247562	+	138	WP_162848650.1	hypothetical protein	-
FJN17_RS34475	2248121..2248267	+	147	WP_162848651.1	hypothetical protein	-
FJN17_RS10310	2248591..2248788	+	198	WP_140479526.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-54)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 10739.26 Da
• Isoelectric Point: 5.1255

>T127566 WP_140479518.1 NZ_CP041090:c2243820-2243527 [Bradyrhizobium symbiodeficiens]
VKLVWSAFAMSDRDGIFTHIEAENPRAAIALDERIAAAARRLVEFPESGRPGRVAGTRELVIVGTPYVAAYTVTESLIRI
LRILHGAQQWPDELPED

Nucleotide

• Length: 294 bp

>T127566 NZ_CP041090:c2243820-2243527 [Bradyrhizobium symbiodeficiens]
GTGAAGCTCGTCTGGTCTGCCTTCGCGATGTCGGACCGCGACGGCATCTTCACTCACATCGAGGCCGAAAATCCTCGGGC
GGCCATCGCGCTCGACGAACGTATCGCCGCGGCTGCGCGTCGACTTGTCGAGTTTCCGGAAAGTGGGCGTCCCGGCCGTG
TCGCCGGCACACGCGAGCTCGTCATTGTCGGCACACCGTATGTCGCTGCCTATACCGTAACGGAAAGCTTGATCCGGATA
TTGCGCATCCTGCACGGCGCCCAGCAATGGCCCGATGAGCTTCCGGAAGATTAA

Antitoxin

Protein

• Length: 103 a.a.
• Molecular weight: 11214.56 Da
• Isoelectric Point: 5.7471

>AT127566 WP_140479520.1 NZ_CP041090:c2244125-2243817 [Bradyrhizobium symbiodeficiens]
MAANALVQTRIDAKVRDRASAVLEGMGLTVSDAVRILLTRTANEGALPLELVTNSKAHDAWFRAKVLEALNDTRPDTSDE
QAEAHFAERRAAARRRTDELES

Nucleotide

• Length: 309 bp

>AT127566 NZ_CP041090:c2244125-2243817 [Bradyrhizobium symbiodeficiens]
ATGGCCGCAAATGCCCTTGTCCAGACCCGCATCGACGCGAAAGTCCGTGATCGCGCATCTGCTGTGCTTGAGGGTATGGG
GCTGACGGTATCGGACGCGGTACGCATCCTGCTGACCCGGACCGCCAACGAGGGCGCGCTGCCGCTCGAACTCGTCACGA
ACAGCAAGGCTCACGACGCCTGGTTTCGCGCGAAGGTTCTGGAAGCGTTGAACGACACACGGCCCGATACCTCTGACGAA
CAGGCCGAGGCGCATTTCGCCGAGCGGCGCGCGGCGGCCCGACGCAGAACGGATGAACTGGAGTCGTGA