Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 428846..429435 Replicon chromosome
Accession NZ_CP041040
Organism Microbacterium foliorum strain M2

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FIV50_RS02145 Protein ID WP_140035991.1
Coordinates 429064..429435 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag FIV50_RS02140 Protein ID WP_140035990.1
Coordinates 428846..429067 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIV50_RS02125 426025..426252 - 228 Protein_421 radical SAM protein -
FIV50_RS02130 426336..427271 + 936 WP_140035988.1 M15 family metallopeptidase -
FIV50_RS02135 427434..428597 + 1164 WP_140035989.1 acyl-CoA dehydrogenase family protein -
FIV50_RS02140 428846..429067 + 222 WP_140035990.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
FIV50_RS02145 429064..429435 + 372 WP_140035991.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
FIV50_RS02150 429597..430169 - 573 WP_140035992.1 ECF transporter S component -
FIV50_RS02155 430286..431161 - 876 WP_140035993.1 siderophore-interacting protein -
FIV50_RS02160 431173..431991 - 819 WP_140035994.1 energy-coupling factor transporter transmembrane protein EcfT -
FIV50_RS02165 431988..433748 - 1761 WP_140035995.1 energy-coupling factor ABC transporter ATP-binding protein -
FIV50_RS02170 433831..434373 - 543 WP_140035996.1 ECF transporter S component -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-120)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13141.32 Da        Isoelectric Point: 11.2458

>T127502 WP_140035991.1 NZ_CP041040:429064-429435 [Microbacterium foliorum]
MTDPSIPLLRRGQIVLVSFDPVIGSETSKTRPAVLVSNNAANAVAMRSPRATVTVVPVTSNIVRLWPFQVLLPADATGLA
QDSKAQAEQVRTVAVTRIVRPIGWVPADLVAAIDDALRLHLSL

Download         Length: 372 bp

>T127502 NZ_CP041040:429064-429435 [Microbacterium foliorum]
ATGACGGATCCATCCATCCCCCTCTTGCGACGGGGGCAGATCGTCCTCGTGTCCTTCGATCCGGTGATCGGATCCGAAAC
GAGCAAGACCAGACCGGCGGTGCTCGTGAGCAACAACGCCGCGAACGCTGTGGCCATGCGGTCACCGCGCGCAACCGTGA
CCGTCGTGCCCGTCACGTCCAACATCGTCCGGCTATGGCCGTTCCAGGTGCTTCTACCCGCCGATGCGACCGGTCTCGCG
CAGGATTCGAAGGCGCAGGCGGAGCAGGTGCGCACCGTCGCCGTCACCAGGATCGTGCGCCCGATCGGCTGGGTGCCGGC
CGATCTCGTCGCCGCGATCGATGATGCCCTTCGACTGCATCTCTCGCTCTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 7790.43 Da        Isoelectric Point: 3.8328

>AT127502 WP_140035990.1 NZ_CP041040:428846-429067 [Microbacterium foliorum]
MTNAKVSLSLSEGDIAFLDLETLSGRYASRSAAVQDAVRLLRESRLADAYAEAFADGYDDEWDAADTDGLASA

Download         Length: 222 bp

>AT127502 NZ_CP041040:428846-429067 [Microbacterium foliorum]
ATGACGAACGCCAAAGTGAGTCTGAGTCTGAGCGAAGGAGATATCGCGTTCCTCGACCTGGAGACACTGAGCGGTAGGTA
CGCCTCTCGCTCGGCCGCGGTCCAGGATGCTGTTCGGCTCCTGCGCGAGAGTCGACTCGCCGATGCTTATGCAGAAGCCT
TCGCCGACGGGTACGACGACGAGTGGGACGCCGCTGACACCGATGGGCTCGCGTCCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References