Detailed information of TA system TA127483

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /GNAT-DUF1778
• Location: 4560925..4561691
• Replicon: chromosome
• Accession: NZ_CP041036
• Organism: Shewanella polaris strain SM1901

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FH971_RS19950
• Protein ID: WP_140235436.1
• Coordinates: 4561194..4561691 (+)
• Length: 166 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FH971_RS19945
• Protein ID: WP_140235435.1
• Coordinates: 4560925..4561197 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FH971_RS19930	4556620..4557852	+	1233	WP_140235432.1	imidazolonepropionase	-
FH971_RS19935	4558144..4558923	+	780	WP_140235433.1	haloacid dehalogenase type II	-
FH971_RS19940	4559109..4560770	+	1662	WP_140235434.1	amidohydrolase	-
FH971_RS19945	4560925..4561197	+	273	WP_140235435.1	DUF1778 domain-containing protein	Antitoxin
FH971_RS19950	4561194..4561691	+	498	WP_140235436.1	GNAT family N-acetyltransferase	Toxin
FH971_RS19955	4561947..4562753	-	807	WP_140235437.1	nucleotide-binding protein	-
FH971_RS19960	4563267..4563506	-	240	WP_137224272.1	YdcH family protein	-
FH971_RS19965	4563685..4565562	+	1878	WP_140235438.1	DUF885 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (86-152)

Antitoxin

• Vibrio phage ICP1, Orf50 (2-89)

Sequences

Toxin

Protein

• Length: 166 a.a.
• Molecular weight: 18493.03 Da
• Isoelectric Point: 6.4801

>T127483 WP_140235436.1 NZ_CP041036:4561194-4561691 [Shewanella polaris]
IMNTVLLDKAKHDRNRFNCGIDALNNYLKIMASQQAKKDNCRTFVLEDDNDNSHIIGFYTLTMTPIDLNALPDKLQKKYQ
SSTSGGLIARLAIDDRYKGQGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGATHFYEHYGFQAFQDAENKLFITIADV
RASLS

Nucleotide

• Length: 498 bp

>T127483 NZ_CP041036:4561194-4561691 [Shewanella polaris]
ATAATGAATACGGTACTTTTAGATAAAGCTAAACACGATAGAAACCGATTCAACTGTGGTATTGATGCTCTTAATAATTA
CTTAAAAATCATGGCGAGTCAGCAAGCAAAGAAAGACAACTGCAGAACGTTTGTTTTAGAAGATGATAACGATAACTCGC
ATATCATCGGCTTTTATACCTTAACAATGACACCAATTGACCTAAATGCTCTGCCGGATAAGCTACAGAAAAAGTATCAA
TCATCAACCTCTGGCGGCCTAATAGCCCGCTTAGCCATCGATGACCGTTATAAAGGCCAAGGCTTTGGCGAATGGTTACT
TATTGATGCACTACGAAAACTGTTAGCGGCAAGTGATAGCGTAGCATTCCCAGTCGTCATTGTTGACGCAAAAGATGGCG
CAACACACTTCTACGAACATTATGGATTTCAGGCCTTTCAAGACGCAGAAAACAAACTGTTCATCACCATTGCAGATGTA
AGAGCAAGCTTAAGTTAA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9782.23 Da
• Isoelectric Point: 6.2988

>AT127483 WP_140235435.1 NZ_CP041036:4560925-4561197 [Shewanella polaris]
MATTLPRITARVDVDTQDLLTKAAAIAGMSSINSFVLSAAIEKAKQVIEREQTLKLNQTDAMLLMEALDSPATPNSKLKT
ASERYESKTQ

Nucleotide

• Length: 273 bp

>AT127483 NZ_CP041036:4560925-4561197 [Shewanella polaris]
ATGGCGACTACTTTACCTCGCATCACCGCTAGAGTTGATGTCGACACCCAAGATTTACTGACAAAGGCTGCAGCTATAGC
GGGTATGTCGAGCATTAACTCATTTGTACTCAGTGCAGCAATCGAAAAAGCCAAACAAGTAATAGAACGTGAACAAACAC
TAAAACTTAACCAAACAGATGCAATGTTGCTTATGGAAGCGTTAGACAGTCCAGCAACACCAAACTCAAAACTCAAAACG
GCTTCGGAACGTTACGAAAGCAAAACCCAATAA