Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 2770246..2771347 Replicon chromosome
Accession NZ_CP041025
Organism Paremcibacter congregatus strain ZYLT

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FIV45_RS12185 Protein ID WP_204602361.1
Coordinates 2770589..2771347 (+) Length 253 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FIV45_RS12180 Protein ID WP_204602359.1
Coordinates 2770246..2770602 (+) Length 119 a.a.

Genomic Context

FIV45_RS12160FIV45_RS12165FIV45_RS12170FIV45_RS12175FIV45_RS12180FIV45_RS12185FIV45_RS12200FIV45_RS12205FIV45_RS12210FIV45_RS12215FIV45_RS12190FIV45_RS12195
Location: 2765314..2766600 (1287 bp)
Type: Others
Protein ID: WP_099472344.1
Location: 2766922..2767137 (216 bp)
Type: Others
Protein ID: WP_099472343.1
Location: 2767156..2768808 (1653 bp)
Type: Others
Protein ID: WP_099472342.1
Location: 2768994..2770166 (1173 bp)
Type: Others
Protein ID: WP_139932340.1
Location: 2770246..2770602 (357 bp)
Type: Antitoxin
Protein ID: WP_204602359.1
Location: 2770589..2771347 (759 bp)
Type: Toxin
Protein ID: WP_204602361.1
Location: 2772244..2773977 (1734 bp)
Type: Others
Protein ID: WP_099471095.1
Location: 2774077..2774632 (556 bp)
Type: Others
Protein ID: Protein_2421
Location: 2774934..2775173 (240 bp)
Type: Others
Protein ID: WP_099471094.1
Location: 2775166..2775576 (411 bp)
Type: Others
Protein ID: WP_099471093.1
Location: 2771374..2771613 (240 bp)
Type: Others
Protein ID: WP_139932342.1
Location: 2771676..2771867 (192 bp)
Type: Others
Protein ID: WP_099471096.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FIV45_RS121602765314..2766600+1287WP_099472344.1hypothetical protein-
FIV45_RS121652766922..2767137+216WP_099472343.1hypothetical protein-
FIV45_RS121702767156..2768808+1653WP_099472342.1recombinase family protein-
FIV45_RS121752768994..2770166+1173WP_139932340.1site-specific integrase-
FIV45_RS121802770246..2770602+357WP_204602359.1DUF2384 domain-containing proteinAntitoxin
FIV45_RS121852770589..2771347+759WP_204602361.1RES domain-containing proteinToxin
FIV45_RS121902771374..2771613-240WP_139932342.1hypothetical protein-
FIV45_RS121952771676..2771867-192WP_099471096.1hypothetical protein-
FIV45_RS122002772244..2773977+1734WP_099471095.1PAS domain S-box protein-
FIV45_RS122052774077..2774632+556Protein_2421IS6 family transposase-
FIV45_RS122102774934..2775173+240WP_099471094.1type II toxin-antitoxin system prevent-host-death family antitoxin-
FIV45_RS122152775166..2775576+411WP_099471093.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(65-215)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(14-63)


Sequences

Toxin        


Download         Length: 253 a.a.        Molecular weight: 28438.49 Da        Isoelectric Point: 5.4052

>T127451 WP_204602361.1 NZ_CP041025:2770589-2771347 [Paremcibacter congregatus]
VEKFNLPSIDLIKTAIVSKIRGIAWRVVESQEEIATLELVDTLEEQAILEGLLEKSKPPLPENCRDLDYLLATPFRYPPL
KWGSRFGRKHEPSLFYGSENIPTALAETAYYRVLFWTGMAEPPPSGTLKTQHTIYSTKYDCSAGLYLNKPPFEEYQDLLQ
HPQDYSGSQKLGTIMRELGVDGFQFISARCPNKGLNIALFTPYALAAKRPDEKQNWICETSEQHIMFSGQGVLFKFNVEG
FQIDGKAPLPAS

Download         Length: 759 bp

>T127451 NZ_CP041025:2770589-2771347 [Paremcibacter congregatus]
GTGGAAAAATTTAATCTTCCCTCAATAGACCTGATTAAAACGGCAATTGTTTCCAAAATTAGGGGTATCGCTTGGCGTGT
TGTGGAAAGTCAGGAAGAAATTGCCACACTGGAACTTGTTGATACGCTGGAAGAACAAGCAATTTTAGAAGGGCTTCTTG
AGAAATCCAAGCCTCCTCTCCCTGAGAACTGTCGTGATCTGGACTATTTATTAGCAACCCCCTTTCGTTATCCCCCCTTA
AAATGGGGTTCCCGATTTGGGCGCAAACATGAGCCTAGTCTTTTTTATGGCTCAGAAAATATTCCAACGGCCCTCGCAGA
AACAGCCTATTACCGGGTTTTATTCTGGACAGGGATGGCGGAACCTCCCCCGTCTGGCACACTTAAAACACAACATACGA
TTTATTCTACAAAATATGACTGTTCGGCTGGATTATATTTAAACAAGCCTCCTTTTGAAGAATATCAGGACTTGCTCCAG
CATCCTCAGGATTATAGTGGATCACAGAAACTTGGCACGATCATGAGAGAATTGGGTGTAGACGGCTTTCAATTCATCTC
CGCACGCTGCCCTAACAAGGGTTTGAATATTGCACTTTTTACCCCTTATGCACTCGCCGCAAAACGACCAGATGAAAAGC
AGAACTGGATATGTGAAACTTCTGAACAGCATATTATGTTTAGCGGACAAGGGGTTTTATTTAAATTTAACGTCGAAGGT
TTCCAAATTGACGGGAAAGCCCCCCTACCCGCCAGCTAA

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13054.13 Da        Isoelectric Point: 8.0738

>AT127451 WP_204602359.1 NZ_CP041025:2770246-2770602 [Paremcibacter congregatus]
MTALTIEETNDELVLAKAVLKTAKALGLTQEELGQILGRDRTSIARGLNPSSKAGELALYLIRCYRSLFVVVGGEAENIK
HWFTTMNHHTNGVPKEQVKNIQGLVHILEYLDAIRGKI

Download         Length: 357 bp

>AT127451 NZ_CP041025:2770246-2770602 [Paremcibacter congregatus]
TTGACGGCTCTAACTATTGAAGAAACCAACGATGAACTTGTTCTGGCAAAGGCTGTTTTAAAAACAGCCAAAGCATTGGG
TTTAACGCAGGAAGAACTCGGTCAAATATTAGGTCGGGACCGTACGTCTATTGCACGCGGTCTAAACCCTTCCAGTAAGG
CGGGAGAACTGGCCCTCTATCTTATTCGCTGTTACCGCTCTTTATTTGTTGTCGTCGGCGGAGAAGCGGAGAATATCAAA
CATTGGTTTACCACCATGAACCACCATACAAATGGTGTCCCCAAAGAACAGGTGAAGAATATTCAAGGTCTTGTCCATAT
TCTTGAATATCTGGATGCCATTCGTGGAAAAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References