Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 2770246..2771347 Replicon chromosome
Accession NZ_CP041025
Organism Paremcibacter congregatus strain ZYLT

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FIV45_RS12185 Protein ID WP_204602361.1
Coordinates 2770589..2771347 (+) Length 253 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FIV45_RS12180 Protein ID WP_204602359.1
Coordinates 2770246..2770602 (+) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIV45_RS12160 2765314..2766600 + 1287 WP_099472344.1 hypothetical protein -
FIV45_RS12165 2766922..2767137 + 216 WP_099472343.1 hypothetical protein -
FIV45_RS12170 2767156..2768808 + 1653 WP_099472342.1 recombinase family protein -
FIV45_RS12175 2768994..2770166 + 1173 WP_139932340.1 site-specific integrase -
FIV45_RS12180 2770246..2770602 + 357 WP_204602359.1 DUF2384 domain-containing protein Antitoxin
FIV45_RS12185 2770589..2771347 + 759 WP_204602361.1 RES domain-containing protein Toxin
FIV45_RS12190 2771374..2771613 - 240 WP_139932342.1 hypothetical protein -
FIV45_RS12195 2771676..2771867 - 192 WP_099471096.1 hypothetical protein -
FIV45_RS12200 2772244..2773977 + 1734 WP_099471095.1 PAS domain S-box protein -
FIV45_RS12205 2774077..2774632 + 556 Protein_2421 IS6 family transposase -
FIV45_RS12210 2774934..2775173 + 240 WP_099471094.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
FIV45_RS12215 2775166..2775576 + 411 WP_099471093.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(65-215)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(14-63)


Sequences

Toxin        


Download         Length: 253 a.a.        Molecular weight: 28438.49 Da        Isoelectric Point: 5.4052

>T127451 WP_204602361.1 NZ_CP041025:2770589-2771347 [Paremcibacter congregatus]
VEKFNLPSIDLIKTAIVSKIRGIAWRVVESQEEIATLELVDTLEEQAILEGLLEKSKPPLPENCRDLDYLLATPFRYPPL
KWGSRFGRKHEPSLFYGSENIPTALAETAYYRVLFWTGMAEPPPSGTLKTQHTIYSTKYDCSAGLYLNKPPFEEYQDLLQ
HPQDYSGSQKLGTIMRELGVDGFQFISARCPNKGLNIALFTPYALAAKRPDEKQNWICETSEQHIMFSGQGVLFKFNVEG
FQIDGKAPLPAS

Download         Length: 759 bp

>T127451 NZ_CP041025:2770589-2771347 [Paremcibacter congregatus]
GTGGAAAAATTTAATCTTCCCTCAATAGACCTGATTAAAACGGCAATTGTTTCCAAAATTAGGGGTATCGCTTGGCGTGT
TGTGGAAAGTCAGGAAGAAATTGCCACACTGGAACTTGTTGATACGCTGGAAGAACAAGCAATTTTAGAAGGGCTTCTTG
AGAAATCCAAGCCTCCTCTCCCTGAGAACTGTCGTGATCTGGACTATTTATTAGCAACCCCCTTTCGTTATCCCCCCTTA
AAATGGGGTTCCCGATTTGGGCGCAAACATGAGCCTAGTCTTTTTTATGGCTCAGAAAATATTCCAACGGCCCTCGCAGA
AACAGCCTATTACCGGGTTTTATTCTGGACAGGGATGGCGGAACCTCCCCCGTCTGGCACACTTAAAACACAACATACGA
TTTATTCTACAAAATATGACTGTTCGGCTGGATTATATTTAAACAAGCCTCCTTTTGAAGAATATCAGGACTTGCTCCAG
CATCCTCAGGATTATAGTGGATCACAGAAACTTGGCACGATCATGAGAGAATTGGGTGTAGACGGCTTTCAATTCATCTC
CGCACGCTGCCCTAACAAGGGTTTGAATATTGCACTTTTTACCCCTTATGCACTCGCCGCAAAACGACCAGATGAAAAGC
AGAACTGGATATGTGAAACTTCTGAACAGCATATTATGTTTAGCGGACAAGGGGTTTTATTTAAATTTAACGTCGAAGGT
TTCCAAATTGACGGGAAAGCCCCCCTACCCGCCAGCTAA

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13054.13 Da        Isoelectric Point: 8.0738

>AT127451 WP_204602359.1 NZ_CP041025:2770246-2770602 [Paremcibacter congregatus]
MTALTIEETNDELVLAKAVLKTAKALGLTQEELGQILGRDRTSIARGLNPSSKAGELALYLIRCYRSLFVVVGGEAENIK
HWFTTMNHHTNGVPKEQVKNIQGLVHILEYLDAIRGKI

Download         Length: 357 bp

>AT127451 NZ_CP041025:2770246-2770602 [Paremcibacter congregatus]
TTGACGGCTCTAACTATTGAAGAAACCAACGATGAACTTGTTCTGGCAAAGGCTGTTTTAAAAACAGCCAAAGCATTGGG
TTTAACGCAGGAAGAACTCGGTCAAATATTAGGTCGGGACCGTACGTCTATTGCACGCGGTCTAAACCCTTCCAGTAAGG
CGGGAGAACTGGCCCTCTATCTTATTCGCTGTTACCGCTCTTTATTTGTTGTCGTCGGCGGAGAAGCGGAGAATATCAAA
CATTGGTTTACCACCATGAACCACCATACAAATGGTGTCCCCAAAGAACAGGTGAAGAATATTCAAGGTCTTGTCCATAT
TCTTGAATATCTGGATGCCATTCGTGGAAAAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References