Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 896552..897306 Replicon chromosome
Accession NZ_CP041025
Organism Paremcibacter congregatus strain ZYLT

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag FIV45_RS03865 Protein ID WP_204601986.1
Coordinates 896552..897052 (-) Length 167 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag FIV45_RS03870 Protein ID WP_099471047.1
Coordinates 897040..897306 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIV45_RS03840 892603..893529 - 927 WP_099471041.1 phenylacetic acid degradation operon negative regulatory protein PaaX -
FIV45_RS03845 893701..894027 - 327 WP_099471042.1 hypothetical protein -
FIV45_RS03850 894288..894620 - 333 WP_099471043.1 hypothetical protein -
FIV45_RS03855 894852..895655 - 804 WP_099471044.1 methyltransferase domain-containing protein -
FIV45_RS03860 895952..896338 + 387 WP_099471045.1 hypothetical protein -
FIV45_RS03865 896552..897052 - 501 WP_204601986.1 GNAT family N-acetyltransferase Toxin
FIV45_RS03870 897040..897306 - 267 WP_099471047.1 DUF1778 domain-containing protein Antitoxin
FIV45_RS03875 897719..898429 - 711 WP_099471048.1 hypothetical protein -
FIV45_RS03880 898563..898796 - 234 WP_204601988.1 helix-turn-helix domain-containing protein -
FIV45_RS03885 899140..900087 + 948 WP_139932307.1 hypothetical protein -
FIV45_RS03890 900135..900860 - 726 WP_099471098.1 acetoacetyl-CoA reductase -
FIV45_RS03895 900921..902096 - 1176 WP_099471099.1 acetyl-CoA C-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(24-146)

Antitoxin

Vibrio phage ICP1, Orf50

(7-80)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18348.32 Da        Isoelectric Point: 9.6409

>T127449 WP_204601986.1 NZ_CP041025:c897052-896552 [Paremcibacter congregatus]
MGKITPPQIMTADHETALFDCGHDTLNEWLQKRALKNQTQDASHSYVVCDGQRVIGYYALSSGSIARLGTPGSLSRNMPD
PIPVMVLGRLAIDRAYQDRKLGAALLKDAMLRTLKVSRIVGVKALLVHALSDEAKRFYLHFAFQVSPVDPMTLLLSVKAI
RSHYDA

Download         Length: 501 bp

>T127449 NZ_CP041025:c897052-896552 [Paremcibacter congregatus]
TTGGGAAAAATAACACCGCCGCAGATCATGACGGCAGATCATGAGACCGCCTTGTTTGACTGTGGCCATGACACCTTGAA
TGAGTGGCTGCAGAAACGGGCGCTCAAAAATCAAACGCAGGACGCCAGCCATAGCTATGTGGTGTGCGACGGTCAACGTG
TGATCGGCTATTACGCCCTGTCCAGCGGTAGCATCGCGCGGTTGGGCACGCCGGGATCTCTATCAAGAAACATGCCGGAC
CCGATCCCGGTCATGGTGCTGGGCAGGCTGGCCATCGACCGGGCGTATCAGGACCGGAAACTGGGGGCCGCCCTGCTGAA
GGACGCCATGCTGCGCACGCTGAAAGTATCCCGGATTGTCGGGGTCAAGGCACTGCTGGTGCATGCGCTGTCCGACGAGG
CGAAGCGGTTTTATCTGCATTTCGCCTTTCAGGTCTCGCCCGTTGACCCGATGACGTTGCTGTTGAGCGTCAAGGCGATC
CGCAGTCATTATGACGCATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9961.36 Da        Isoelectric Point: 5.0980

>AT127449 WP_099471047.1 NZ_CP041025:c897306-897040 [Paremcibacter congregatus]
MSKTAAINMRVEPAQHDLVTRAAAMLHTDRSSFIMSVACREAENVLLDQRIFSLEDDAFQALQEVLNAPVEEHDRLRKLL
TGPSPWEK

Download         Length: 267 bp

>AT127449 NZ_CP041025:c897306-897040 [Paremcibacter congregatus]
ATGTCCAAAACAGCCGCCATCAATATGCGGGTGGAGCCCGCCCAGCATGATCTGGTGACCCGGGCCGCCGCCATGCTTCA
TACCGACCGGAGCAGCTTTATCATGTCCGTTGCCTGCCGTGAGGCGGAGAATGTCCTGCTGGATCAGCGCATCTTCTCTC
TGGAGGACGACGCCTTTCAGGCCCTGCAGGAGGTGCTCAACGCCCCGGTGGAAGAGCATGACCGGTTGCGGAAATTACTG
ACCGGGCCGTCGCCTTGGGAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References