Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2039150..2039295 Replicon chromosome
Accession NZ_CP041022
Organism Klebsiella pneumoniae strain KP1677

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2039186..2039288 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2039150..2039295 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FH977_RS09940 2034282..2036341 + 2060 Protein_1911 oligopeptidase B -
FH977_RS09945 2036345..2037003 - 659 Protein_1912 exodeoxyribonuclease X -
FH977_RS09950 2037082..2037312 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FH977_RS09955 2037425..2037799 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FH977_RS09960 2037803..2038672 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
FH977_RS09965 2038689..2039027 + 339 WP_016529031.1 YebY family protein -
- 2039150..2039295 - 146 - - Antitoxin
- 2039186..2039288 + 103 - - Toxin
FH977_RS09975 2039663..2039806 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FH977_RS09980 2039911..2040879 - 969 WP_004151446.1 VirK/YbjX family protein -
FH977_RS09985 2041036..2041602 + 567 WP_094935968.1 metallophosphoesterase -
FH977_RS09990 2041599..2041790 - 192 WP_002911395.1 YebW family protein -
FH977_RS09995 2041888..2042127 - 240 WP_002911393.1 YebV family protein -
FH977_RS10000 2042243..2043676 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T127437 NZ_CP041022:2039186-2039288 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT127437 NZ_CP041022:c2039295-2039150 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References