Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4477490..4477635 Replicon chromosome
Accession NZ_CP040993
Organism Klebsiella pneumoniae strain FDAARGOS_775

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4477497..4477599 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4477490..4477635 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIU12_RS22055 4473022..4474455 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FIU12_RS22060 4474571..4474810 + 240 WP_002911393.1 YebV family protein -
FIU12_RS22065 4474908..4475099 + 192 WP_025860695.1 YebW family protein -
FIU12_RS22070 4475096..4475749 - 654 WP_032443931.1 protein-serine/threonine phosphatase -
FIU12_RS22075 4475906..4476874 + 969 WP_073980558.1 DUF535 family protein -
FIU12_RS27520 4476979..4477122 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4477490..4477635 + 146 - - Antitoxin
- 4477497..4477599 - 103 - - Toxin
FIU12_RS22085 4477758..4478096 - 339 WP_002911404.1 YebY family protein -
FIU12_RS22090 4478113..4478982 - 870 WP_025860697.1 copper homeostasis membrane protein CopD -
FIU12_RS22095 4478986..4479360 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FIU12_RS22100 4479473..4479703 + 231 WP_025860700.1 DNA polymerase III subunit theta -
FIU12_RS22105 4479782..4480441 + 660 WP_021440386.1 exodeoxyribonuclease X -
FIU12_RS22110 4480445..4482505 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T127327 NZ_CP040993:c4477599-4477497 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT127327 NZ_CP040993:4477490-4477635 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References