Detailed information of TA system TA127314

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 59750..60312
• Replicon: plasmid unnamed1
• Accession: NZ_CP040989
• Organism: Vibrio furnissii strain FDAARGOS_777

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: FIU11_RS00345
• Protein ID: WP_038152854.1
• Coordinates: 60010..60312 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: FIU11_RS00340
• Protein ID: WP_004729600.1
• Coordinates: 59750..59995 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FIU11_RS00315	55464..56531	-	1068	WP_081454518.1	recombinase RecT	-
FIU11_RS00320	56614..57081	-	468	WP_004729597.1	hypothetical protein	-
FIU11_RS00325	57332..57559	-	228	WP_038152853.1	hypothetical protein	-
FIU11_RS00330	57789..58712	+	924	WP_004729598.1	IS5 family transposase	-
FIU11_RS00335	58752..59549	-	798	WP_004729599.1	recombinase family protein	-
FIU11_RS00340	59750..59995	+	246	WP_004729600.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FIU11_RS00345	60010..60312	+	303	WP_038152854.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FIU11_RS00350	60309..60911	-	603	WP_004729602.1	recombinase family protein	-
FIU11_RS00355	61521..62597	-	1077	WP_038152856.1	replication initiation protein	-
FIU11_RS00360	63541..64263	+	723	WP_004729604.1	hypothetical protein	-
FIU11_RS00365	64253..65002	+	750	WP_038152858.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..76098	76098
	-	flank	IS/Tn	-	-	57789..58712	923

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-89)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-56)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11644.32 Da
• Isoelectric Point: 6.7572

>T127314 WP_038152854.1 NZ_CP040989:60010-60312 [Vibrio furnissii]
MSSYKLSPLAQSDLTDIRRYTIEHWGSTQWSVYFNELQESMSLLASNELIGIQIPEMGERYYRFPLKHHVIYYITQEDHI
VIVAVLGKHMSPAKHFASIS

Nucleotide

• Length: 303 bp

>T127314 NZ_CP040989:60010-60312 [Vibrio furnissii]
ATGAGCAGTTATAAGCTTTCACCTTTAGCCCAGTCTGATCTCACTGATATTCGTCGTTACACCATAGAACATTGGGGCAG
TACTCAATGGTCCGTCTATTTTAATGAATTACAGGAATCGATGTCATTGCTGGCAAGTAACGAACTGATCGGAATTCAGA
TCCCGGAAATGGGAGAGCGATACTACCGTTTTCCTCTGAAGCACCATGTGATTTATTACATCACTCAGGAAGACCATATC
GTTATCGTCGCTGTGCTGGGTAAGCATATGTCTCCTGCAAAACATTTTGCGTCTATTTCTTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9115.57 Da
• Isoelectric Point: 4.5702

>AT127314 WP_004729600.1 NZ_CP040989:59750-59995 [Vibrio furnissii]
MQSLTANTAKTKFGDLLMKVQREPVQISKNGSPVAVMMSCEEYEQLEALKMMLVKSRFEQAEIDIRNGDLVDGDEFMKSL
A

Nucleotide

• Length: 246 bp

>AT127314 NZ_CP040989:59750-59995 [Vibrio furnissii]
ATGCAATCATTAACAGCAAATACAGCAAAAACCAAATTTGGCGATTTACTGATGAAGGTTCAGCGTGAACCCGTGCAAAT
CAGTAAAAATGGCTCACCGGTTGCGGTGATGATGTCCTGTGAAGAATATGAGCAATTAGAAGCACTCAAGATGATGCTGG
TTAAATCTCGTTTTGAACAGGCAGAAATTGATATCAGGAATGGCGATCTGGTCGATGGTGATGAATTTATGAAATCTCTG
GCTTAA