127304

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 3033136..3033662 Replicon chromosome
Accession NZ_CP040932
Organism Oceanicola sp. D3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FHY55_RS15160 Protein ID WP_140014993.1
Coordinates 3033405..3033662 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FHY55_RS15155 Protein ID WP_140014992.1
Coordinates 3033136..3033408 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FHY55_RS15145 3028206..3030185 + 1980 WP_140014990.1 DNA primase -
FHY55_RS15150 3030340..3032343 + 2004 WP_140014991.1 RNA polymerase sigma factor RpoD -
FHY55_RS15155 3033136..3033408 + 273 WP_140014992.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FHY55_RS15160 3033405..3033662 + 258 WP_140014993.1 Txe/YoeB family addiction module toxin Toxin
FHY55_RS15165 3033666..3034022 + 357 WP_140014994.1 YigZ family protein -
FHY55_RS15170 3034027..3034281 + 255 WP_140014995.1 hypothetical protein -
FHY55_RS15175 3034298..3034606 + 309 WP_140014996.1 DUF1294 domain-containing protein -
FHY55_RS15180 3034596..3035267 - 672 WP_140014997.1 SDR family oxidoreductase -
FHY55_RS15185 3035325..3036140 - 816 WP_140014998.1 YmdB family metallophosphoesterase -
FHY55_RS15190 3036328..3036879 - 552 WP_140014999.1 5-formyltetrahydrofolate cyclo-ligase -
FHY55_RS15195 3036876..3038285 - 1410 WP_140015000.1 magnesium transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9903.27 Da        Isoelectric Point: 9.7679

>T127304 WP_140014993.1 NZ_CP040932:3033405-3033662 [Oceanicola sp. D3]
MNVTFTAEAWSHYTYWQKADKKLTAKINALIKECQRHPFDGTGKPEALRGDLSGFWSRRINHEHRLVYRIHGGAVEIVAC
RYHYG

Download         Length: 258 bp

>T127304 NZ_CP040932:3033405-3033662 [Oceanicola sp. D3]
ATGAACGTTACCTTCACCGCCGAGGCTTGGAGCCACTACACCTACTGGCAGAAGGCCGACAAGAAACTCACCGCCAAGAT
CAATGCCCTGATAAAAGAATGCCAGCGCCATCCCTTCGATGGCACGGGCAAGCCTGAAGCGCTGAGAGGCGACCTGTCCG
GCTTCTGGTCTCGCCGTATCAACCACGAGCATCGGCTGGTCTATCGCATCCATGGCGGCGCAGTAGAGATCGTCGCCTGC
CGCTACCACTACGGCTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9828.24 Da        Isoelectric Point: 4.4536

>AT127304 WP_140014992.1 NZ_CP040932:3033136-3033408 [Oceanicola sp. D3]
MKHASSTDLRKNLSAMMDAVTADHEPLLVTRAGGKPVVMLSLEDYEAMDETTYLLANPANAAMLRRSIAQLDTAETVTKT
MDELDAMAKE

Download         Length: 273 bp

>AT127304 NZ_CP040932:3033136-3033408 [Oceanicola sp. D3]
ATGAAACACGCCTCCTCCACCGACCTGCGCAAGAACCTCTCGGCCATGATGGATGCCGTCACCGCCGATCATGAGCCGCT
ACTCGTCACCCGCGCGGGCGGCAAGCCGGTGGTGATGCTCTCGCTCGAAGACTACGAGGCGATGGACGAAACCACTTACC
TTCTGGCCAACCCGGCCAATGCGGCGATGTTGCGCCGGTCCATCGCCCAACTCGATACCGCCGAGACTGTCACCAAGACC
ATGGATGAATTGGATGCCATGGCCAAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References