Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-couple_hipB
Location 2912596..2913204 Replicon chromosome
Accession NZ_CP040932
Organism Oceanicola sp. D3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FHY55_RS14510 Protein ID WP_140014879.1
Coordinates 2912596..2912847 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FHY55_RS14515 Protein ID WP_140014880.1
Coordinates 2912860..2913204 (+) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FHY55_RS14490 2907819..2909027 + 1209 WP_140016123.1 sugar ABC transporter permease -
FHY55_RS14495 2909027..2909803 + 777 WP_140014876.1 sugar ABC transporter ATP-binding protein -
FHY55_RS14500 2909803..2911242 + 1440 WP_140014877.1 xylulokinase -
FHY55_RS14505 2911239..2912543 + 1305 WP_140014878.1 xylose isomerase -
FHY55_RS14510 2912596..2912847 + 252 WP_140014879.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FHY55_RS14515 2912860..2913204 + 345 WP_140014880.1 helix-turn-helix transcriptional regulator Antitoxin
FHY55_RS20565 2913268..2913438 + 171 WP_168223018.1 hypothetical protein -
FHY55_RS14520 2913501..2914724 + 1224 WP_140014881.1 FAD-binding oxidoreductase -
FHY55_RS14525 2914832..2915380 + 549 WP_140014882.1 fasciclin domain-containing protein -
FHY55_RS14535 2915605..2917257 - 1653 WP_140014883.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-79)

Antitoxin

Cro/C1-type helix-turn-helix domain

(58-112)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9021.43 Da        Isoelectric Point: 11.3629

>T127303 WP_140014879.1 NZ_CP040932:2912596-2912847 [Oceanicola sp. D3]
MIDIRYTRAAAKALSRLPANTRDRIRSKIEAFAANPASQANNVTALKGREGIRLRVGAWRVIMSDEGVVLAVLDVGPRGG
IYD

Download         Length: 252 bp

>T127303 NZ_CP040932:2912596-2912847 [Oceanicola sp. D3]
TTGATAGACATCCGCTACACCCGTGCCGCCGCCAAGGCGCTGTCCCGTCTGCCCGCCAACACGCGCGATCGCATCCGCTC
GAAGATCGAAGCCTTCGCCGCAAATCCGGCGTCGCAGGCCAACAATGTCACCGCCCTCAAGGGCCGCGAAGGCATTCGGC
TTCGGGTTGGCGCGTGGCGGGTTATCATGAGTGACGAGGGCGTGGTGCTGGCCGTGCTCGATGTCGGGCCGCGTGGTGGC
ATTTATGACTGA

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12215.68 Da        Isoelectric Point: 4.5594

>AT127303 WP_140014880.1 NZ_CP040932:2912860-2913204 [Oceanicola sp. D3]
MNETVTIPRADYEALVEASELLADLQAHDTARSALATGAEELLPTHVANRLIDGDNPLRVYREHRGLTQVALSEASGVNR
VQIADIESGRKTGSVTTLRKLADALSVGLDDLVP

Download         Length: 345 bp

>AT127303 NZ_CP040932:2912860-2913204 [Oceanicola sp. D3]
ATGAATGAAACCGTCACCATCCCCCGCGCCGATTACGAAGCGCTTGTGGAAGCCTCCGAGCTGCTGGCCGACCTTCAGGC
CCATGACACGGCCCGCAGCGCCCTCGCCACCGGCGCGGAAGAACTGCTGCCCACCCATGTCGCCAACCGCCTGATTGATG
GCGACAACCCGCTGCGCGTCTATCGCGAGCACCGCGGGCTGACTCAGGTCGCACTCTCCGAGGCCTCCGGCGTCAACCGT
GTGCAAATCGCCGACATCGAATCCGGCCGCAAAACCGGCTCGGTTACGACCCTGCGCAAGCTCGCCGATGCCCTCTCGGT
CGGCCTCGACGACCTCGTGCCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References