Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4515783..4516352 Replicon chromosome
Accession NZ_CP040930
Organism Pseudomonas sp. SWI7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FH041_RS20740 Protein ID WP_080992810.1
Coordinates 4515783..4516091 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FH041_RS20745 Protein ID WP_049695410.1
Coordinates 4516122..4516352 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FH041_RS20710 4511964..4512374 + 411 WP_027915709.1 pilin -
FH041_RS20725 4513146..4514545 + 1400 Protein_4027 PAAR domain-containing protein -
FH041_RS20730 4514538..4514927 + 390 WP_049695408.1 hypothetical protein -
FH041_RS20735 4515005..4515526 - 522 WP_049695409.1 cysteine hydrolase -
FH041_RS20740 4515783..4516091 - 309 WP_080992810.1 tRNA(fMet)-specific endonuclease VapC Toxin
FH041_RS20745 4516122..4516352 - 231 WP_049695410.1 antitoxin Antitoxin
FH041_RS20750 4516804..4517334 + 531 WP_028688070.1 ATPase AAA -
FH041_RS20755 4517353..4519311 - 1959 WP_049695411.1 response regulator -
FH041_RS20760 4519523..4521298 + 1776 WP_049695412.1 sensor domain-containing phosphodiesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-92)

Antitoxin

SpoVT-AbrB domain

(8-51)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11333.94 Da        Isoelectric Point: 6.4630

>T127300 WP_080992810.1 NZ_CP040930:c4516091-4515783 [Pseudomonas sp. SWI7]
MCISTVTLMELIYGAEKSSNPERNLAAVEDLAARLEVLTYDRNAAAHTGQLRAELARLGTPIGPFDQMIAGHARSQGLII
VTNNRREFERVPGLRSEDWVIR

Download         Length: 309 bp

>T127300 NZ_CP040930:c4516091-4515783 [Pseudomonas sp. SWI7]
ATGTGCATAAGCACCGTCACCTTGATGGAGTTGATCTATGGTGCTGAGAAATCCTCGAATCCCGAGCGTAATCTAGCAGC
GGTTGAAGACCTGGCAGCGCGCTTGGAAGTTCTTACATATGATAGAAACGCTGCCGCCCACACTGGACAGCTCCGTGCTG
AATTGGCACGTTTGGGCACGCCTATTGGCCCTTTCGATCAAATGATCGCTGGTCACGCTCGCTCACAAGGTCTGATTATT
GTCACTAATAACCGTCGTGAGTTTGAGCGAGTACCTGGACTGCGGAGCGAAGACTGGGTTATCCGATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8615.57 Da        Isoelectric Point: 4.4230

>AT127300 WP_049695410.1 NZ_CP040930:c4516352-4516122 [Pseudomonas sp. SWI7]
MEQGAVFLSNRSQAIRLPKAAAFSEDVKRVDVVAIGRTRIITPAGEAWDSWFNDLAPTEDFMAERDQSADQERERF

Download         Length: 231 bp

>AT127300 NZ_CP040930:c4516352-4516122 [Pseudomonas sp. SWI7]
ATGGAACAAGGTGCCGTTTTTTTGAGTAATCGTAGCCAAGCTATAAGACTGCCCAAAGCTGCAGCATTTTCGGAAGACGT
CAAGCGCGTTGACGTCGTCGCGATTGGGCGCACACGCATCATCACACCTGCCGGGGAAGCATGGGATAGCTGGTTCAACG
ACTTAGCCCCTACAGAAGATTTCATGGCAGAGCGTGATCAGTCGGCTGATCAAGAGCGCGAGCGTTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References