Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3530309..3530837 Replicon chromosome
Accession NZ_CP040930
Organism Pseudomonas sp. SWI7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FH041_RS16165 Protein ID WP_028688165.1
Coordinates 3530309..3530608 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I1ERU0
Locus tag FH041_RS16170 Protein ID WP_028688166.1
Coordinates 3530598..3530837 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FH041_RS16135 3526341..3526523 - 183 Protein_3150 hypothetical protein -
FH041_RS16140 3526516..3526845 + 330 Protein_3151 integrase -
FH041_RS16145 3526954..3528099 + 1146 WP_140174860.1 DUF4935 domain-containing protein -
FH041_RS16155 3529294..3529476 + 183 Protein_3153 type II toxin-antitoxin system HicA family toxin -
FH041_RS16160 3529564..3530010 + 447 WP_140175143.1 type II toxin-antitoxin system HicB family antitoxin -
FH041_RS16165 3530309..3530608 - 300 WP_028688165.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FH041_RS16170 3530598..3530837 - 240 WP_028688166.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FH041_RS16175 3531256..3532413 - 1158 WP_110607259.1 HAMP domain-containing histidine kinase -
FH041_RS16180 3532406..3533218 - 813 WP_140174862.1 alpha/beta hydrolase -
FH041_RS16185 3533556..3533762 + 207 WP_140174864.1 DUF3079 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3522466..3530837 8371


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11578.45 Da        Isoelectric Point: 10.2270

>T127298 WP_028688165.1 NZ_CP040930:c3530608-3530309 [Pseudomonas sp. SWI7]
MTYSLEFDARALKEWQKLGDTIRQQLKKKLASVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAIDK
REREQAYHKAAERVLSKTS

Download         Length: 300 bp

>T127298 NZ_CP040930:c3530608-3530309 [Pseudomonas sp. SWI7]
ATGACCTATAGCCTTGAGTTCGATGCGAGAGCGCTGAAGGAATGGCAGAAGCTTGGGGATACGATCCGGCAACAACTCAA
GAAAAAACTCGCCTCGGTTTTGCTAAATCCCAGAGTCGAAGCGAACCGGCTACACAGCTTGCCGGATTGCTACAAGATCA
AGCTGCGCAGTAGCGGCTACCGATTGGTCTATCAGGTGATCGATCAGGAGGTTGTTGTATTTGTGGTAGCTATCGATAAG
CGCGAACGAGAGCAGGCTTATCACAAGGCAGCCGAGCGAGTCTTGAGTAAAACGTCATGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9128.45 Da        Isoelectric Point: 4.6182

>AT127298 WP_028688166.1 NZ_CP040930:c3530837-3530598 [Pseudomonas sp. SWI7]
MASINVRIDDDLKTRAYRELERLGVTPSELMRQALQYVAERGQLPFRPVLMTDEDETLLATVRERLADPQRVKVSLDDL

Download         Length: 240 bp

>AT127298 NZ_CP040930:c3530837-3530598 [Pseudomonas sp. SWI7]
ATGGCCTCCATCAACGTCCGCATCGACGACGATCTCAAAACCCGAGCCTACCGTGAGCTCGAGCGCTTGGGCGTGACGCC
CTCGGAGCTCATGCGTCAGGCATTACAGTACGTGGCCGAGCGTGGACAGCTACCGTTCAGGCCTGTGCTCATGACGGATG
AGGATGAAACGCTGCTGGCGACCGTCCGCGAGCGCCTTGCCGACCCTCAGCGAGTGAAGGTTTCTCTGGATGACCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References