Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2794999..2795504 Replicon chromosome
Accession NZ_CP040915
Organism Georgenia sp. Z443

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FE374_RS12790 Protein ID WP_139929579.1
Coordinates 2795244..2795504 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FE374_RS12785 Protein ID WP_139929577.1
Coordinates 2794999..2795247 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE374_RS12760 2790458..2790757 - 300 WP_139929567.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
FE374_RS12765 2790868..2791284 - 417 WP_139929569.1 pilus assembly protein CpaE -
FE374_RS12770 2791420..2792709 + 1290 WP_139929571.1 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase family protein -
FE374_RS12775 2792738..2793259 - 522 WP_139929573.1 GNAT family N-acetyltransferase -
FE374_RS12780 2793424..2794911 + 1488 WP_139929575.1 flotillin family protein -
FE374_RS12785 2794999..2795247 + 249 WP_139929577.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FE374_RS12790 2795244..2795504 + 261 WP_139929579.1 Txe/YoeB family addiction module toxin Toxin
FE374_RS12795 2795783..2797318 + 1536 WP_139929581.1 FAD binding domain-containing protein -
FE374_RS12800 2797315..2799732 + 2418 WP_139929583.1 xanthine dehydrogenase molybdopterin binding subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10386.78 Da        Isoelectric Point: 9.3511

>T127224 WP_139929579.1 NZ_CP040915:2795244-2795504 [Georgenia sp. Z443]
VRIVFAPQAWEDYTYWQRVDRSLVKRINRLIDDIARDPHEGIGKPEPLKYGLANAWSRRITDEHRLVYVVRDDDHLLLQA
RYHYAR

Download         Length: 261 bp

>T127224 NZ_CP040915:2795244-2795504 [Georgenia sp. Z443]
GTGAGGATCGTCTTCGCCCCGCAGGCATGGGAGGACTACACCTACTGGCAGCGAGTCGACCGCTCCCTCGTCAAGCGGAT
CAACCGATTGATCGACGACATTGCCCGGGATCCCCACGAGGGCATCGGCAAACCTGAGCCGCTCAAGTACGGTCTCGCCA
ACGCCTGGTCCAGGCGCATCACCGACGAGCACCGCCTGGTCTACGTCGTCCGCGACGACGACCACCTTCTCCTTCAAGCG
CGCTACCACTACGCCCGGTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9194.21 Da        Isoelectric Point: 4.2910

>AT127224 WP_139929577.1 NZ_CP040915:2794999-2795247 [Georgenia sp. Z443]
MPITASEARKNLFPLIEEVNDDRSVVEITSKRGNAVLMAADDYAAWQETAYLFRSPANARRLLDAMEAVDRGEGAEHDLD
RE

Download         Length: 249 bp

>AT127224 NZ_CP040915:2794999-2795247 [Georgenia sp. Z443]
ATGCCCATCACCGCCAGCGAGGCCCGCAAGAACCTTTTCCCCTTGATCGAGGAGGTCAACGACGACCGCTCAGTCGTCGA
GATTACCTCCAAACGCGGCAATGCCGTCCTGATGGCTGCGGACGACTACGCGGCATGGCAGGAGACCGCCTACCTCTTCC
GCTCCCCTGCCAACGCCCGGCGCCTGCTCGATGCCATGGAGGCGGTCGACCGCGGTGAGGGCGCCGAGCACGACCTCGAC
CGCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References