Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2138868..2139514 Replicon chromosome
Accession NZ_CP040915
Organism Georgenia sp. Z443

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FE374_RS09680 Protein ID WP_139928599.1
Coordinates 2139095..2139514 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FE374_RS09675 Protein ID WP_139928597.1
Coordinates 2138868..2139098 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE374_RS09645 2134554..2134871 + 318 WP_139928587.1 oxidoreductase -
FE374_RS09650 2134926..2136401 - 1476 WP_139928589.1 leucyl aminopeptidase -
FE374_RS09655 2136447..2136800 + 354 WP_139928591.1 hypothetical protein -
FE374_RS09660 2136905..2137300 + 396 WP_139931507.1 hypothetical protein -
FE374_RS09665 2137371..2138270 + 900 WP_139928593.1 hypothetical protein -
FE374_RS09670 2138386..2138784 + 399 WP_139928595.1 DUF2695 domain-containing protein -
FE374_RS09675 2138868..2139098 + 231 WP_139928597.1 hypothetical protein Antitoxin
FE374_RS09680 2139095..2139514 + 420 WP_139928599.1 PIN domain-containing protein Toxin
FE374_RS09685 2139761..2140030 - 270 WP_139928601.1 hypothetical protein -
FE374_RS09690 2140905..2141312 + 408 WP_139928603.1 hypothetical protein -
FE374_RS09695 2141318..2142457 + 1140 WP_139931508.1 RNA polymerase subunit sigma-24 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(3-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15217.25 Da        Isoelectric Point: 6.1266

>T127222 WP_139928599.1 NZ_CP040915:2139095-2139514 [Georgenia sp. Z443]
VTRFLLDSNVLIAATIAEHEHHDAAATWLADAEGFAVCPVVEGALVRFLMRIGESGDTASRILAAVRSHPRSQFWPDAVS
YVDVALSRIRGHRQVTDAYLARLASSKGSLLATFDTTLAELWPDQTMLIPHEKTHSPDV

Download         Length: 420 bp

>T127222 NZ_CP040915:2139095-2139514 [Georgenia sp. Z443]
GTGACCCGTTTCCTGCTCGACTCCAACGTCCTGATCGCTGCCACCATCGCCGAGCACGAGCATCACGACGCGGCCGCGAC
GTGGCTGGCTGACGCAGAGGGGTTCGCGGTCTGCCCCGTCGTCGAAGGGGCGCTGGTGCGTTTCCTTATGCGCATCGGCG
AGTCCGGGGACACTGCATCCCGGATTCTCGCGGCCGTCCGAAGCCACCCGCGAAGCCAGTTCTGGCCCGATGCCGTCTCT
TACGTGGACGTCGCGCTCTCCCGGATCCGAGGACATCGGCAGGTGACGGACGCGTACCTTGCTCGGCTCGCATCGAGCAA
GGGGAGCCTCCTGGCGACGTTTGACACCACCCTGGCGGAGTTATGGCCGGACCAGACAATGCTCATTCCACACGAGAAAA
CGCATTCGCCGGACGTGTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8086.26 Da        Isoelectric Point: 5.7524

>AT127222 WP_139928597.1 NZ_CP040915:2138868-2139098 [Georgenia sp. Z443]
MRTTVDLPPAVHQRARQLAAVQGKSLSAVIADLTIRGLAQLDTPLRLRVDERTGLPVLSVGRSVTDADVAEALEDA

Download         Length: 231 bp

>AT127222 NZ_CP040915:2138868-2139098 [Georgenia sp. Z443]
ATGCGCACGACGGTGGATCTACCTCCCGCCGTGCACCAGCGTGCTCGTCAGCTCGCTGCCGTGCAGGGCAAGTCCCTATC
GGCCGTAATAGCCGACCTCACCATCCGTGGCCTCGCCCAGCTCGATACGCCTCTGCGGCTGCGTGTCGATGAGCGGACCG
GGTTGCCGGTCCTGTCCGTAGGCCGCAGCGTCACCGACGCGGACGTGGCAGAGGCACTGGAAGACGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References