Detailed information of TA system TA127205

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 80965..81590
• Replicon: plasmid pCFSAN074387
• Accession: NZ_CP040901
• Organism: Salmonella enterica subsp. enterica serovar Typhimurium strain SAP18-6199

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: FF984_RS24165
• Protein ID: WP_000911322.1
• Coordinates: 80965..81363 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: FF984_RS24170
• Protein ID: WP_000450265.1
• Coordinates: 81363..81590 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FF984_RS24150	77057..77551	+	495	WP_010999946.1	entry exclusion protein	-
FF984_RS24155	77587..78318	+	732	WP_000782438.1	complement resistance protein TraT	-
FF984_RS24160	78695..80956	+	2262	WP_015589607.1	type IV conjugative transfer system coupling protein TraD	-
FF984_RS24165	80965..81363	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
FF984_RS24170	81363..81590	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93930	93930

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HipA-like, C-terminal (149-401)

Antitoxin

• Cro/C1-type helix-turn-helix domain (18-69)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T127205 WP_000911322.1 NZ_CP040901:c81363-80965 [Salmonella enterica subsp. enterica serovar Typhimurium]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T127205 NZ_CP040901:c81363-80965 [Salmonella enterica subsp. enterica serovar Typhimurium]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT127205 WP_000450265.1 NZ_CP040901:c81590-81363 [Salmonella enterica subsp. enterica serovar Typhimurium]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT127205 NZ_CP040901:c81590-81363 [Salmonella enterica subsp. enterica serovar Typhimurium]
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